Profiling of single‐cell transcriptomes

W Chen, V Gardeux, A Meireles‐Filho… - Current protocols in …, 2017 - Wiley Online Library
Complex biological systems are composed of multiple cell types whose transcriptional
activity can vary due to differences in cell state, environmental stimulation, or intrinsic …

Single-Cell Transcriptome Profiling

G Shapira, N Shomron - Deep Sequencing Data Analysis, 2021 - Springer
Over the last decade, single cell RNA sequencing (scRNAseq) became an increasingly
viable solution for analyzing cellular heterogeneity and cell-specific expression differences …

Quantitative single-cell transcriptomics

C Ziegenhain, B Vieth, S Parekh… - Briefings in …, 2018 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) is currently transforming our understanding of
biology, as it is a powerful tool to resolve cellular heterogeneity and molecular networks …

Beyond bulk: a review of single cell transcriptomics methodologies and applications

A Kulkarni, AG Anderson, DP Merullo… - Current opinion in …, 2019 - Elsevier
Highlights•Technologies such as single-cell RNA sequencing have rapidly progressed in
recent years.•Various methods exist for preparing libraries for sequencing, each with its own …

[HTML][HTML] A hitchhiker's guide to single-cell transcriptomics and data analysis pipelines

R Nayak, Y Hasija - Genomics, 2021 - Elsevier
Single-cell transcriptomics (SCT) is a tour de force in the era of big omics data that has led to
the accumulation of massive cellular transcription data at an astounding resolution of single …

scRNASeqDB: a database for RNA-Seq based gene expression profiles in human single cells

Y Cao, J Zhu, P Jia, Z Zhao - Genes, 2017 - mdpi.com
Single-cell RNA sequencing (scRNA-Seq) is rapidly becoming a powerful tool for high-
throughput transcriptomic analysis of cell states and dynamics at the single cell level. Both …

[HTML][HTML] An accessible, interactive GenePattern Notebook for analysis and exploration of single-cell transcriptomic data

CK Mah, AT Wenzel, EF Juarez, T Tabor… - …, 2018 - ncbi.nlm.nih.gov
Single-cell RNA sequencing (scRNA-seq) has emerged as a popular method to profile gene
expression at the resolution of individual cells. While there have been methods and software …

[HTML][HTML] Identifying cell populations with scRNASeq

TS Andrews, M Hemberg - Molecular aspects of medicine, 2018 - Elsevier
Single-cell RNASeq (scRNASeq) has emerged as a powerful method for quantifying the
transcriptome of individual cells. However, the data from scRNASeq experiments is often …

Interactive single cell RNA-Seq analysis with the Single Cell Toolkit (SCTK)

DF Jenkins, T Faits, E Briars, S Carrasco Pro… - BioRxiv, 2018 - biorxiv.org
Single cell RNA-sequencing (scRNA-Seq) allows researchers to profile transcriptional
activity in individual cells. However, the complex nature of these data and variability in study …

ASAP: a web-based platform for the analysis and interactive visualization of single-cell RNA-seq data

V Gardeux, FPA David, A Shajkofci, PC Schwalie… - …, 2017 - academic.oup.com
Motivation Single-cell RNA-sequencing (scRNA-seq) allows whole transcriptome profiling of
thousands of individual cells, enabling the molecular exploration of tissues at the cellular …