Given the heterogeneity of senescent cells, our knowledge of both the drivers and
consequences of cellular senescence in tissues and organs remains limited, as is our …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the global
pandemic of coronavirus disease 2019 (COVID-19) and particularly exhibits severe …

Abstract Coronavirus Disease 2019 (COVID-19) is caused by the novel coronavirus, Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …

The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more
than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020 …

Abstract Corona virus disease 2019 (COVID-19) is a global emergency able to overwhelm
the healthcare capacities worldwide and to affect the older generation especially. When …

The elderly may represent a specific cluster of high-risk patients for developing COVID-19
with rapidly progressive clinical deterioration. Indeed, in older individuals …

Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest …

Human coronaviruses (hCoVs) cause severe respiratory illness in the elderly. Age-related
impairments in innate immunity and suboptimal virus-specific T cell and antibody responses …

Aging is characterized by the dynamic remodeling of the immune system designated
“immunosenescence,” and is associated with altered hematopoiesis, thymic involution, and …

A central clinical question as the world deals with the COVID-19 pandemic is what the long-
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …