Colorectal cancer (CRC) is a serious public health problem and non-invasive biomarkers
improving diagnosis or therapy are strongly required. Circulating cell-free DNA (cfDNA) has …

Background Colorectal cancer is the most common malignancy and the third leading cause
of cancer-related death worldwide. This study aimed to identify potential diagnostic …

Background Early detection of colorectal carcinoma (CRC) would help to identify tumors
when curative treatments are available and beneficial. However, current screening methods …

Background Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an
increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has …

Circulating tumor DNA (ctDNA) has emerged as a useful diagnostic and prognostic
biomarker in many cancers. Here, we conducted a study to investigate the potential use of …

Abstract Background Circulating tumor DNA (ctDNA) is a promising diagnostic and
prognostic marker for many cancers and has been actively investigated in recent years …

Background Colorectal cancer is the fourth cause of cancer-related deaths worldwide,
though detection at early stages associates with good prognosis. Thus, there is a clear …

Screening for early‐stage disease is vital for reducing colorectal cancer (CRC)‐related
mortality. Methylation of circulating tumor DNA has been previously used for various types of …

Genome-wide DNA hypomethylation plays an important role in epigenomic and genomic
instability and colorectal carcinogenesis. DNA methylation in the long interspersed …

Background Cell-free circulating tumour-derived DNA (ctDNA) can be detected by testing for
methylated BCAT1 and IKZF1 DNA, which has proven sensitivity for colorectal cancer …