[HTML][HTML] SARS-CoV-2 productively infects human brain microvascular endothelial cells

RC Yang, K Huang, HP Zhang, L Li, YF Zhang… - Journal of …, 2022 - Springer
Background The emergence of the novel, pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused a global health emergency. SARS-CoV-2 is highly …

[HTML][HTML] SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and
model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the …

[HTML][HTML] Human brain microvascular endothelial cells exposure to SARS-CoV-2 leads to inflammatory activation through NF-κB non-canonical pathway and …

CS Motta, S Torices, BG da Rosa, AC Marcos… - Viruses, 2023 - mdpi.com
Neurological effects of COVID-19 and long-COVID-19, as well as neuroinvasion by SARS-
CoV-2, still pose several questions and are of both clinical and scientific relevance. We …

COVID-19 and Long COVID: Disruption of the Neurovascular Unit, Blood-Brain Barrier, and Tight Junctions

D Kempuraj, KK Aenlle, J Cohen… - The …, 2023 - journals.sagepub.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), could affect brain structure and function. SARS-CoV …

[HTML][HTML] SARS-CoV-2 poorly replicates in cells of the human blood-brain barrier without associated deleterious effects

O Constant, J Barthelemy, K Bollore, E Tuaillon… - Frontiers in …, 2021 - frontiersin.org
Various neurological symptoms have been associated to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection including headache, fever, anosmia, ageusia, but …

[HTML][HTML] Neurological complications associated with the blood-brain barrier damage induced by the inflammatory response during SARS-CoV-2 infection

I Alquisiras-Burgos, I Peralta-Arrieta… - Molecular …, 2021 - Springer
The main discussion above of the novel pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and …

[PDF][PDF] The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2

S Krasemann, U Haferkamp, S Pfefferle, MS Woo… - Stem cell reports, 2022 - cell.com
Neurological complications are common in COVID-19. Although SARS-CoV-2 has been
detected in patients' brain tissues, its entry routes and resulting consequences are not well …

[HTML][HTML] Alteration of the blood-brain barrier by COVID-19 and its implication in the permeation of drugs into the brain

H Hernández-Parra, OD Reyes-Hernández… - Frontiers in Cellular …, 2023 - frontiersin.org
Diverse neurological symptoms have been reported in patients with SARS-CoV-2 disease
(COVID-19), including stroke, ataxia, meningitis, encephalitis, and cognitive impairment …

[HTML][HTML] COVID-19 and cognitive impairment: neuroinvasive and blood‒brain barrier dysfunction

Y Chen, W Yang, F Chen, L Cui - Journal of Neuroinflammation, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has led to a global pandemic. Although COVID-19 …

[HTML][HTML] SARS-CoV-2 deregulates the vascular and immune functions of brain pericytes via Spike protein

R Khaddaj-Mallat, N Aldib, M Bernard… - Neurobiology of …, 2021 - Elsevier
Abstract Coronavirus disease 19 (COVID-19) is a respiratory illness caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2). COVID-19 pathogenesis causes …