Biomarkers of ageing and frailty may predict COVID-19 severity

KJ Wanhella, C Fernandez-Patron - Ageing research reviews, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is caused by the novel coronavirus, Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …

COVID-19 mortality as a fingerprint of biological age

MC Polidori, H Sies, L Ferrucci, T Benzing - Ageing research reviews, 2021 - Elsevier
Abstract Corona virus disease 2019 (COVID-19) is a global emergency able to overwhelm
the healthcare capacities worldwide and to affect the older generation especially. When …

Biological aging predicts vulnerability to COVID-19 severity in UK Biobank participants

CL Kuo, LC Pilling, JL Atkins, JAH Masoli… - The Journals of …, 2021 - academic.oup.com
Background Age and disease prevalence are the 2 biggest risk factors for Coronavirus
disease 2019 (COVID-19) symptom severity and death. We therefore hypothesized that …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

[HTML][HTML] Why does COVID-19 disproportionately affect older people?

AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …

[HTML][HTML] covid-19 in elderly adults: clinical features, molecular mechanisms, and proposed strategies

Y Yang, Y Zhao, F Zhang, L Zhang, L Li - Aging and disease, 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is causing problems worldwide. Most
people are susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Age-related vulnerability to coronavirus disease 2019 (COVID-19): biological, contextual, and policy-related factors

EM Crimmins - Public Policy & Aging Report, 2020 - academic.oup.com
The detailed facts surrounding the coronavirus disease 2019 (COVID-19) pandemic are still
evolving; however, one of the most shocking aspects of the COVID-19 pandemic is how …

How can biology of aging explain the severity of COVID-19 in older adults

A Gallo, E Pero, S Pellegrino… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
In December 2019 a cluster of pneumonia caused by a previous unknown coronavirus,
SARS-CoV-2, was identified in Wuhan, China. 1 SARS-CoV-2 belongs to the subgenus of …

[HTML][HTML] Increased pace of aging in COVID-related mortality

F Galkin, A Parish, E Bischof, J Zhang, P Mamoshina… - Life, 2021 - mdpi.com
Identifying prognostic biomarkers and risk stratification for COVID-19 patients is a
challenging necessity. One of the core survival factors is patient age. However …

Frailty trajectories in community‐dwelling older adults during COVID‐19 pandemic: The PRESTIGE study

A Pilotto, C Custodero, S Zora, S Poli… - European Journal of …, 2022 - Wiley Online Library
Background Frailty has been recognized as potential surrogate of biological age and
relevant risk factor for COVID‐19 severity. Thus, it is important to explore the frailty …