Adaptive metabolic and inflammatory responses identified using accelerated aging metrics are linked to adverse outcomes in severe SARS-CoV-2 infection
A Márquez-Salinas, CA Fermín-Martínez… - The Journals of …, 2021 - academic.oup.com
Background Chronological age (CA) is a predictor of adverse coronavirus disease 2019
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
COVID-19 and Frailty
T Ciarambino, P Crispino, G Minervini, M Giordano - Vaccines, 2023 - mdpi.com
Older age is a major risk factor for adverse outcomes of COVID-19, potentially due to
immunosenescence and chronic low-grade inflammation, both characteristics of older adults …
immunosenescence and chronic low-grade inflammation, both characteristics of older adults …
COVID-19 in older adults
A Nanda, NVRK Vura, S Gravenstein - Aging clinical and experimental …, 2020 - Springer
The advent of the SARS-CoV-2 and COVID-19 pandemic has generated a lot of publications
at a rapid pace. We know that older adults disproportionately suffer the most severe of …
at a rapid pace. We know that older adults disproportionately suffer the most severe of …
Geriatric syndromes and SARS-Cov-2: more than just being old
I Aprahamian, M Cesari - The Journal of frailty & aging, 2020 - Springer
128 biological background (eg, the so-called phenomenon of inflamm-aging); all aspects
that can complicate the course of disease, much more than the mere number of years lived …
that can complicate the course of disease, much more than the mere number of years lived …
The role of frailty on adverse outcomes among older patients with COVID-19
Background Diagnosis and screening of frailty, a condition characterized by an increased
vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool …
vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool …
Aging in COVID-19: Vulnerability, immunity and intervention
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
[HTML][HTML] From causes of aging to death from COVID-19
MV Blagosklonny - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
COVID-19 is not deadly early in life, but mortality increases exponentially with age, which is
the strongest predictor of mortality. Mortality is higher in men than in women, because men …
the strongest predictor of mortality. Mortality is higher in men than in women, because men …
Functional decline, long term symptoms and course of frailty at 3-months follow-up in COVID-19 older survivors, a prospective observational cohort study
S Prampart, S Le Gentil, ML Bureau, C Macchi… - BMC geriatrics, 2022 - Springer
Background Aging is one of the most important prognostic factors increasing the risk of
clinical severity and mortality of COVID-19 infection. However, among patients over 75 …
clinical severity and mortality of COVID-19 infection. However, among patients over 75 …
[HTML][HTML] Patterns of comorbidity and in-hospital mortality in older patients with COVID-19 infection
M Mahmoud, L Carmisciano, L Tagliafico… - Frontiers in …, 2021 - frontiersin.org
Introduction: Older adults are more susceptible to severe COVID-19, with increased all-
cause mortality. This has been attributed to their multimorbidity and disability. However, it …
cause mortality. This has been attributed to their multimorbidity and disability. However, it …
COVID‐19 is an emergent disease of aging
COVID‐19 is an ongoing pandemic caused by the SARS‐CoV‐2 coronavirus that poses one
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …