[HTML][HTML] COVID-19: risk accumulation among biologically and socially vulnerable older populations

A Calderón-Larrañaga, S Dekhtyar, DL Vetrano… - Ageing research …, 2020 - Elsevier
Emerging data show that the health and economic impacts of COVID-19 are being
disproportionately borne by individuals who are not only biologically, but also socially …

[HTML][HTML] How does SARS-CoV-2 targets the elderly patients? A review on potential mechanisms increasing disease severity

A Smorenberg, EJG Peters, PLA van Daele… - European Journal of …, 2021 - Elsevier
Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest …

Divergent: age, frailty, and atypical presentations of COVID-19 in hospitalized patients

PCE Poco, MJR Aliberti, MB Dias… - The Journals of …, 2021 - academic.oup.com
Background Although frailty has been associated with atypical manifestations of infections,
little is known about COVID-19 presentations in hospitalized frail patients. We aimed to …

Age, host response, and mortality in COVID-19

VC Veiga, AB Cavalcanti - European Respiratory Journal, 2023 - Eur Respiratory Soc
Extract Increased age is a strong risk factor for mortality in patients with coronavirus disease
2019 (COVID-19)[1, 2]. Risk of death increases 1.5 times for every 10 years [1]. Among the …

Long-term effects of hospitalization for COVID-19 on frailty and quality of life in older adults≥ 80 years

M Covino, A Russo, S Salini, G De Matteis… - Journal of Clinical …, 2022 - mdpi.com
Objectives: This study aimed to assess the effects of frailty and the perceived quality of life
(QOL) on the long-term survival (at least 1 year) of patients≥ 80 years hospitalized for …

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: considerations beyond chronological …

OY Bello-Chavolla, A González-Díaz… - The Journals of …, 2021 - academic.oup.com
Background COVID-19 has had a disproportionate impact on older adults. Mexico's
population is younger, yet COVID-19's impact on older adults is comparable to countries …

The relationship between frailty, nutritional status, co-morbidity, CT-body composition and systemic inflammation in patients with COVID-19

J McGovern, Y Al-Azzawi, O Kemp, P Moffitt… - Journal of translational …, 2022 - Springer
Background Frailty, determined by the Canadian Study of Health and Aging-Clinical Frailty
Scale (CFS), is strongly associated with clinical outcomes including mortality in patients with …

Causal association of epigenetic aging and COVID-19 severity and susceptibility: A bidirectional Mendelian randomization study

W Xu, F Zhang, Y Shi, Y Chen, B Shi, G Yu - Frontiers in Medicine, 2022 - frontiersin.org
Observational data from China, the United States, France, and Italy suggest that
chronological age is an adverse COVID-19 outcome risk factor, with older patients having a …

Estimating older adult mortality from COVID-19

A Sharma - The Journals of Gerontology: Series B, 2021 - academic.oup.com
Objectives The purpose of this study was to employ simulations to model the probability of
mortality from COVID-19 (ie, coronavirus) for older adults in the United States given at best …

Biomarkers in long COVID-19: A systematic review

YJ Lai, SH Liu, S Manachevakul, TA Lee… - Frontiers in …, 2023 - frontiersin.org
Purpose Long COVID, also known as post-acute sequelae of COVID-19, refers to the
constellation of long-term symptoms experienced by people suffering persistent symptoms …