[HTML][HTML] Relationship of tobacco smoking and smoking-related DNA methylation with epigenetic age acceleration
X Gao, Y Zhang, LP Breitling, H Brenner - Oncotarget, 2016 - ncbi.nlm.nih.gov
Recent studies have identified biomarkers of chronological age based on DNA methylation
levels. Since active smoking contributes to a wide spectrum of aging-related diseases in …
levels. Since active smoking contributes to a wide spectrum of aging-related diseases in …
Smoking-related DNA methylation is associated with DNA methylation phenotypic age acceleration: The veterans affairs normative aging study
DNA methylation may play a critical role in aging and age-related diseases. DNA
methylation phenotypic age (DNAmPhenoAge) is a new aging biomarker and predictor of …
methylation phenotypic age (DNAmPhenoAge) is a new aging biomarker and predictor of …
The effect of tobacco smoking differs across indices of DNA methylation-based aging in an African American sample: DNA methylation-based indices of smoking …
Smoking is one of the leading preventable causes of morbidity and mortality worldwide,
prompting interest in its association with DNA methylation-based measures of biological …
prompting interest in its association with DNA methylation-based measures of biological …
Epigenetic signatures of starting and stopping smoking
Background Multiple studies have made robust associations between differential DNA
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
methylation and exposure to cigarette smoke. But whether a DNA methylation phenotype is …
Smoking and blood DNA methylation: an epigenome-wide association study and assessment of reversibility
PA Dugué, CH Jung, JE Joo, X Wang, EM Wong… - Epigenetics, 2020 - Taylor & Francis
We conducted a genome-wide association study of blood DNA methylation and smoking,
attempted replication of previously discovered associations, and assessed the reversibility of …
attempted replication of previously discovered associations, and assessed the reversibility of …
Healthy lifestyle, DNA methylation age acceleration, and incident risk of coronary heart disease
Background DNA methylation clocks emerged as a tool to determine biological aging and
have been related to mortality and age-related diseases. Little is known about the …
have been related to mortality and age-related diseases. Little is known about the …
[HTML][HTML] DNA methylation age of blood predicts future onset of lung cancer in the women's health initiative
Lung cancer is considered an age-associated disease, whose progression is in part due to
accumulation of genomic instability as well as age-related decline in system integrity and …
accumulation of genomic instability as well as age-related decline in system integrity and …
DNA methylation as a biomarker of aging in epidemiologic studies
Cancer is largely an aging disease. Accelerated biological aging may be the strongest
predictor of cancer and other chronic disease risks. In the absence of reliable and …
predictor of cancer and other chronic disease risks. In the absence of reliable and …
Dynamic DNA methylation during aging: a “prophet” of age-related outcomes
FH Xiao, HT Wang, QP Kong - Frontiers in genetics, 2019 - frontiersin.org
The biological markers of aging used to predict physical health status in older people are of
great interest. Telomere shortening, which occurs during the process of cell replication, was …
great interest. Telomere shortening, which occurs during the process of cell replication, was …
Obesity accelerates epigenetic aging in middle-aged but not in elderly individuals
T Nevalainen, L Kananen, S Marttila, J Jylhävä… - Clinical …, 2017 - Springer
Background Human aging is associated with profound changes in one of the major
epigenetic mechanisms, DNA methylation. Some of these changes occur in a clock-like …
epigenetic mechanisms, DNA methylation. Some of these changes occur in a clock-like …