Individuals with intact cognition and neuropathology consistent with Alzheimer's disease
(AD) are referred to as asymptomatic AD (AsymAD). These individuals are highly likely to …

Neuropsychiatric symptoms (NPS) such as depression, apathy, aggression, and psychosis
are now recognized as core features of Alzheimer's disease (AD), and there is a general …

It remains unclear what clinical features inform the accuracy of a clinical diagnosis of
Alzheimer disease (AD). Data were obtained from the National Alzheimer's Coordinating …

Older adults with intact cognition before death and substantial Alzheimer disease (AD)
lesions at autopsy have been termed “asymptomatic AD subjects”(ASYMAD). We previously …

Objective To develop an algorithm that separates patients with Alzheimer disease (AD) from
controls. Design Longitudinal case-control study. Setting The Texas Alzheimer's Research …

While the clinical and neuropathological characterization of Alzheimer's Disease (AD) is well
defined, our understanding of the progression of pathologic mechanisms in AD remains …

Background: Alzheimer's disease (AD), the most common form of dementia, is a progressive
neurodegenerative disorder with interrelated molecular, physiological, anatomical …

Abstract The Alzheimer's Disease Sequencing Project (ADSP) undertook whole exome
sequencing in 5,740 late-onset Alzheimer disease (AD) cases and 5,096 cognitively normal …

No single-omic approach completely elucidates the multitude of alterations taking place in
Alzheimer's disease (AD). Here, we coupled transcriptomic and phosphoproteomic …

Background Alzheimer's disease (AD) is associated with abnormal tau and amyloid-β
accumulation in the brain, leading to neurofibrillary tangles, neuropil threads and …