Immunological changes associated with aging play a major role in both the blunted
responses to infections as well as to vaccines intended to prevent many of these infections …

Age-related declines in immune response pose a challenge in combating diseases later in
life. Influenza (flu) infection remains a significant burden on older populations and often …

Effective vaccine‐induced immune responses are particularly essential in older adults who
face an increased risk of immunosenescence. However, the complexity and variability of the …

The elderly have clearly been found to have both increased risk and severity of infections.
Immunosenescence, the state of dysregulated immune function with aging, is felt to be a …

The world's population is aging, which brings about huge scientific challenges. Since the
biological process of aging is by far the greatest risk factor for most chronic diseases …

Background Aging is characterized by a progressive decline in the capacity of the immune
system to fight influenza virus infection and to respond to vaccination. Among the several …

The goal of annual influenza vaccination is to reduce mortality and morbidity associated with
this disease through the generation of protective immune responses. The objective of the …

Numerous studies have explored whether the antibody response to influenza vaccination in
elderly adults is as strong as it is in young adults. Results vary, but tend to indicate lower …

Immunosenescence contributes materially to the decreased ability of the elderly to control
infectious disease, which is also reflected in their generally poor response to vaccination …

Vaccination is the most effective measure to protect against infections. However, with
increasing age, there is a progressive decline in the ability of the immune system to both …