Contextual adversity, telomere erosion, pubertal development, and health: Two models of accelerated aging, or one?

J Belsky, I Shalev - Development and Psychopathology, 2016 - cambridge.org
Two independent lines of inquiry suggest that growing up under conditions of contextual
adversity (eg, poverty and household chaos) accelerates aging and undermines long-term …

Early-life stress and reproductive cost: A two-hit developmental model of accelerated aging?

I Shalev, J Belsky - Medical Hypotheses, 2016 - Elsevier
Two seemingly independent bodies of research suggest a two-hit model of accelerated
aging, one highlighting early-life stress and the other reproduction. The first, informed by …

How does early‐life adversity shape telomere dynamics during adulthood? Problems and paradigms

V Marasco, S Smith, F Angelier - BioEssays, 2022 - Wiley Online Library
Although early‐life adversity has been associated with negative consequences during
adulthood, growing evidence shows that such adversity can also lead to subsequent stress …

Psychosocial stressors and telomere length: a current review of the science

KE Rentscher, JE Carroll… - Annual review of public …, 2020 - annualreviews.org
A growing literature suggests that exposure to adverse social conditions may accelerate
biological aging, offering one mechanism through which adversity may increase risk for age …

Early-life adversity accelerates child and adolescent development

J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

Stress, telomeres, and psychopathology: toward a deeper understanding of a triad of early aging

ES Epel, AA Prather - Annual review of clinical psychology, 2018 - annualreviews.org
Telomeres play an important part in aging and show relationships to lifetime adversity,
particularly childhood adversity. Meta-analyses demonstrate reliable associations between …

Telomere dynamics may link stress exposure and ageing across generations

MF Haussmann, BJ Heidinger - Biology letters, 2015 - royalsocietypublishing.org
Although exposure to stressors is known to increase disease susceptibility and accelerate
ageing, evidence is accumulating that these effects can span more than one generation …

An intricate dance: Life experience, multisystem resiliency, and rate of telomere decline throughout the lifespan

E Puterman, E Epel - Social and personality psychology …, 2012 - Wiley Online Library
Accumulation of life stressors predicts accelerated development and progression of
diseases of aging. Telomere length, the DNA‐based biomarker indicating cellular aging, is a …

Stress and telomere biology: a lifespan perspective

I Shalev, S Entringer, PD Wadhwa… - …, 2013 - Elsevier
In the past decade, the growing field of telomere science has opened exciting new avenues
for understanding the cellular and molecular substrates of stress and stress-related aging …

The fetal programming of telomere biology hypothesis: an update

S Entringer, K de Punder, C Buss… - … Transactions of the …, 2018 - royalsocietypublishing.org
Research on mechanisms underlying fetal programming of health and disease risk has
focused primarily on processes that are specific to cell types, organs or phenotypes of …