Differentiating monozygotic twins using NGS

C Skrant, I Grabylnikov, KM Elkins, CB Zeller - Next Generation Sequencing …, 2024 - Elsevier
Monozygotic twins are difficult to differentiate in a forensic laboratory because they share
identical short tandem repeat DNA profiles. To help solve this problem, multiple new studies …

Differentiating between monozygotic twins in forensics through next generation mtGenome sequencing

Z Wang, S Zhang, Y Bian, C Li - Forensic Science International: Genetics …, 2015 - Elsevier
Monozygotic (MZ) twins, considered being genetically identical, cannot be distinguished one
from another by forensic short tandem repeat (STR) profiling. The high mutation rate of the …

[PDF][PDF] Identification of monozygotic twins in the era of next‑‑generation sequencing

A Masny, B Wysocka - clkp.policja.pl
Monozygotic twins pose a challenge to forensic science due to the lack of standardized tools
to differentiate them within a pair, and thus making it difficult or impossible for a court to …

[PDF][PDF] Cracking the code: Can forensic genetics distinguish identical twins? A technical perspective

AR Kattamreddy - 2023 - account.sljfmsl.sljol.info
ABSTRACT DNA fingerprinting has revolutionized the field of forensic investigation in recent
times. The utility of DNA fingerprinting technology in differentiating between monozygotic …

Identification of the perpetrator among identical twins using next-generation sequencing technology: A case report

L Yuan, X Chen, Z Liu, Q Liu, A Song, G Bao… - Forensic Science …, 2020 - Elsevier
Background Monozygotic (MZ) twins, considered genetically identical, cannot be
distinguished using regular short tandem repeats (STR) typing, thus presenting a challenge …

Differentiating between monozygotic twins through next-generation mitochondrial genome sequencing

Z Wang, R Zhu, S Zhang, Y Bian, D Lu, C Li - Analytical biochemistry, 2015 - Elsevier
Monozygotic (MZ) twins, considered to be genetically identical, cannot be distinguished from
one another by standard forensic DNA testing. A recent study employed whole genome …

Monozygotic twins: Identical or distinguishable for science and law?

S Turrina, E Bortoletto, G Giannini… - Medicine, Science and …, 2021 - journals.sagepub.com
Monozygotic twins, also known as monovular twins, share an identical genetic heritage
because they are two individuals who derive from the same zygote. For this reason, they …

Twin-pred: a method to distinguish monozygotic twins in forensic science application

G Esposito - 2022 - iris.sissa.it
Monozygotic (MZ) twins discrimination in forensic science remains an unsolved point.
Nowadays, conventional DNA profiling techniques use the analysis of the Short tandem …

Discrimination of monozygotic twins using mtDNA heteroplasmy through probe capture enrichment and massively parallel sequencing

Y Zhong, K Zeng, A Adnan, YZ Li, X Hou, Y Pan… - International Journal of …, 2023 - Springer
Differentiating between monozygotic (MZ) twins remains difficult because they have the
same genetic makeup. Applying the traditional STR genotyping approach cannot …

A genome-wide scan of DNA methylation markers for distinguishing monozygotic twins

Q Du, G Zhu, G Fu, X Zhang, L Fu, S Li… - Twin Research and …, 2015 - cambridge.org
Identification of individuals within pairs of monozygotic (MZ) twins remains unresolved using
common forensic DNA typing technology. For some criminal cases involving MZ twins as …