The dysregulation of cellular metabolism is a hallmark of ageing. To understand the
metabolic changes that occur as a consequence of the ageing process and to find …

The world is aging and we must face the challenges that this brings. One of the reasons for
the increasing aging of the world's population is the increase in life expectancy and, since …

Epigenetics of Aging and Longevity provides an in-depth analysis of the epigenetic nature of
aging and the role of epigenetic factors in mediating the link between early-life experiences …

The role of epigenetics in aging and age-related diseases is a key issue in molecular
physiology and medicine because certain epigenetic factors are thought to mediate, at least …

Mammalian aging can be delayed with genetic, dietary, and pharmacologic approaches.
Given that the elderly population is dramatically increasing and that aging is the greatest risk …

In this contribution to the series of reflective essays celebrating the 25th anniversary of The
FASEB Journal, our task is to assess the growth of research on the biology of aging during …

The field of aging research has progressed rapidly over the past few decades. Genetic
modulators of aging rate that are conserved over a broad evolutionary distance have now …

Aging is intimately linked to system‐wide metabolic changes that can be captured in blood.
Understanding biological processes of aging in humans could help maintain a healthy aging …

After a long and sometimes painful incubation period, biochemical research on aging has
done what we all do eventually: It's come of age. The goal of the field is a deeper …

We conducted a genome-wide association study of 1320 centenarians from the New
England Centenarian Study (median age= 104 years) and 2899 unrelated controls using> 9 …