The original theory of the multi-step process of colorectal cancer (CRC), suggesting that the
disease resulted from the accumulation of mutations in oncogenes and tumor suppressor …

Colorectal cancer (CRC) is one of the most common cancer worldwide and results from the
accumulation of mutations and epimutations in colonic mucosa cells ultimately leading to …

Colorectal cancer (CRC) results from a stepwise accumulation of genetic and epigenetic
alterations that transform the normal colonic epithelium into cancer. DNA methylation …

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. It results from an
accumulation of genetic and epigenetic changes in colon epithelial cells, which transforms …

Despite the recent advances in the therapeutic modalities, colorectal cancer (CRC) remains
to be one of the most common causes of cancer-related death. CRC arises through …

Colorectal cancer (CRC) is a common malignancy. It arises from benign neoplasms and
evolves into adenocarcinomas through a stepwise histological progression sequence …

Colorectal cancer (CRC) develops through a multistage process that results from the
progressive accumulation of genetic mutations, and frequently as a result of mutations in the …

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. One of the
fundamental processes driving the initiation and progression of CRC is the accumulation of …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Colorectal Cancer (CRC) is the commonest cancer in non-smokers posing a significant
health burden in the UK. Observational studies lend support to the impact of environmental …