At the current time, the field of vaccinology remains empirical in many respects. Vaccine
development, vaccine immunogenicity, and vaccine efficacy have, for the most part …

Vaccines, like drugs and medical procedures, are increasingly amenable to individualization
or personalization, often based on novel data resulting from high throughput “omics” …

In this article we define vaccinomics as the integration of immunogenetics and
immunogenomics with systems biology and immune profiling. Vaccinomics is based on the …

In this issue of Immunity, a collection of detailed reviews summarizes needs, opportunities,
and roadblocks to the development of new vaccines, all in the context of our current …

The next 'golden age'in vaccinology will be ushered in by the new science of vaccinomics. In
turn, this will inform and allow the development of personalized vaccines, based on our …

Vaccines have drastically reduced the mortality and morbidity of many diseases. However,
vaccines have historically been developed empirically, and recent development of vaccines …

Each year, vaccine-preventable diseases kill thousands of adults, both in the United States
and across the planet, causing a significant human toll and severe economic burden on the …

Vaccines are public health interventions aimed at preventing infections-related mortality,
morbidity, and disability. While vaccines have been successfully designed for those …

Homo sapiens are genetically diverse, but dramatic demographic and socioeconomic
changes during the past century have created further diversification with respect to age …

The immune system is a network of specialized cell types and tissues that communicates via
cytokines and direct contact, to orchestrate specific types of defensive responses. Until …