Y Dong, Y Huang, B Gutin, A Raed, Y Dong, H Zhu - Scientific reports, 2017 - nature.com
Emerging evidence suggests that epigenetics regulates telomere dynamics in adults. However, the relationship between these pathways in children and youth remains unknown …
Y Lee, D Sun, APS Ori, AT Lu, A Seeboth… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Telomere length is associated with age-related diseases and is highly heritable. It is unclear, however, to what extent epigenetic modifications are associated with leukocyte telomere …
BH Chen, CL Carty, M Kimura, JD Kark, W Chen… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Both leukocyte telomere length (LTL) and DNA methylation age are strongly associated with chronological age. One measure of DNA methylation age-the extrinsic epigenetic age …
The frequency of chromosomal aberrations in peripheral blood predicts a probable cancer risk. The individual telomere length and methylation of repetitive elements may be …
EE Pearce, R Alsaggaf, S Katta, C Dagnall, G Aubert… - Geroscience, 2022 - Springer
Telomere length (TL) and DNA methylation–based epigenetic clocks are markers of biological age, but the relationship between the two is not fully understood. Here, we used …
Background Telomere length is indicative of biological age. Shorter telomeres have been associated with several disease and health states. There are inconsistencies throughout the …
J Lin, E Epel, J Cheon, C Kroenke, E Sinclair… - Journal of …, 2010 - Elsevier
Telomeres are the DNA–protein complexes that protect the ends of eukaryotic chromosomes. The cellular enzyme telomerase counteracts telomere shortening by adding …
J Lin, J Cheon, R Brown, M Coccia… - Journal of …, 2016 - Wiley Online Library
Telomeres, the protective DNA‐protein complexes at the ends of linear chromosomes, are important for genome stability. Leukocyte or peripheral blood mononuclear cell (PBMC) …
K Nordfjäll, U Svenson, KF Norrback, R Adolfsson… - PLoS …, 2009 - journals.plos.org
Age-associated telomere shortening is a well documented feature of peripheral blood cells in human population studies, but it is not known to what extent these data can be transferred …