Senescence is the consequence of a signaling mechanism activated in stressed cells to
prevent proliferation of cells with damage. Senescent cells (Sncs) often develop a …

Senescent cells accumulate with aging and at etiological sites of multiple diseases,
including those accounting for most morbidity, mortality, and health costs. Senescent cells …

Cellular senescence is a major contributor to age-related diseases in humans; however, it
also has a beneficial role in physiological and pathological processes, including wound …

Cellular senescence is a hallmark of aging defined by stable exit from the cell cycle in
response to cellular damage and stress. Senescent cells (SnCs) can develop a …

The concept of geroscience is that since ageing is the greatest risk factor for many diseases
and conditions, targeting the ageing process itself will have the greatest impact on human …

Cellular senescence (CS) is one of hallmarks of aging and accumulation of senescent cells
(SCs) with age contributes to tissue or organismal aging, as well as the pathophysiologies of …

Interlinked and fundamental aging processes appear to be a root-cause contributor to many
disorders and diseases. One such process is cellular senescence, which entails a state of …

The increasing life expectancy of the world population has become an economic and global
public health problem. Increased life expectancy tracks with a higher incidence of multiple …

Aging is the most important single risk factor for many chronic diseases such as cancer,
metabolic syndrome, and neurodegenerative disorders. Targeting aging itself might …

Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …