Aging is one of the most important biological processes and is a known risk factor for many
age-related diseases in human. Studying age-related transcriptomic changes in tissues …

Aging is an inevitable outcome of life, characterized by a progressive decline in tissue and
organ function. At a molecular level, it is marked by the gradual alterations of biomolecules …

Aging is a complex process that can be characterized by functional and cognitive decline in
an individual. Aging can be assessed based on the functional capacity of vital organs and …

Aging is the biggest risk factor for cancer, but the mechanisms linking these two processes
remain unclear. Using GTEx and TCGA data, we compared genes differentially expressed …

Genome-wide studies of aging have identified subsets of genes that show age-related
changes in expression. Although the types of genes that are age regulated vary among …

Aging is the single largest risk factor for chronic disease. Studies in model organisms have
identified conserved pathways that modulate aging rate and the onset and progression of …

By combining transcriptomic data with other data sources, inferences can be made about
functional changes during ageing. Thus, we conducted a meta-analysis on 127 publicly …

Disease epidemiology during ageing shows a transition from cancer to degenerative chronic
disorders as dominant contributors to mortality in the old. Nevertheless, it has remained …

To understand the changes in gene expression that occur as a result of age, which might
create a permissive or causal environment for age-related diseases, we produce a multi …

Motivation: Numerous microarray studies of aging have been conducted, yet given the noisy
nature of gene expression changes with age, elucidating the transcriptional features of …