Early-life tobacco exposure serves as a non-negligible risk factor for aging-related diseases.
To understand the underlying mechanisms, we explored the associations of early-life …

Background Ageing traits and frailty are important health issues in modern medicine.
Evidence supporting the causal effects of tobacco smoking on various ageing traits is …

Background Lung aging is characterized by a number of structural alterations including
fibrosis, chronic inflammation and the alteration of inflammatory cell composition. Chronic …

Background Cigarette smoke is a major public health concern. Epigenetic aging may be an
important pathway by which exposure to cigarette smoke affects health. However, little is …

Knowing the biological age of the neonates enables us to evaluate and better understand
the health and maturity comprehensively. However, because of dearth of biomarkers, it is …

The early-life exposome influences future health and accelerated biological aging has been
proposed as one of the underlying biological mechanisms. We investigated the association …

PhenoAge and BioAge are two commonly used biological age (BA) measures. The author
here searched for gene‐environment interactions (GxE) and gene‐gene interactions (GxG) …

Smoking-associated DNA methylation (DNAm) signatures are reproducible among studies
of mostly European descent, with mixed evidence if smoking accelerates epigenetic aging …

Objective This retrospective cross-sectional study was designed to explore whether the
experience of childhood adversity was associated with epigenetic age acceleration in mid …

Background Smoking leads to the aging of organs. However, no studies have been
conducted to quantify the effect of smoking on the aging of respiratory organs and the aging …