Elevated C-reactive protein levels are associated with prevalent dementia in the oldest-old

BA Kravitz, MM Corrada, CH Kawas - Alzheimer's & Dementia, 2009 - Elsevier
BACKGROUND: C-reactive protein (CRP) is a nonspecific marker of inflammation that is
increased in the brain and serum of patients with Alzheimer's disease (AD), and has been …

Longitudinal associations between C-reactive protein and cognitive performance in normative cognitive ageing and dementia

NA Lewis, JE Knight - Age and Ageing, 2021 - academic.oup.com
Background systemic inflammation appears to play an important role in the pathogenesis
and expression of Alzheimer's disease and other dementias. Previous research has found …

Is there a relationship between high C-reactive protein (CRP) levels and dementia?

A Mancinella, M Mancinella, G Carpinteri… - Archives of gerontology …, 2009 - Elsevier
Inflammation is believed to play a pivotal role in dementia, but its role is still unclear. The aim
of our study was to analyze the interplay among markers of inflammation, such as fibrinogen …

Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease

M Yarchoan, N Louneva, SX Xie, FJ Swenson… - Journal of the …, 2013 - Elsevier
C-reactive protein (CRP) participates in the systemic response to inflammation. Previous
studies report inconsistent findings regarding the relationship between plasma CRP and …

C-reactive protein predicts incidence of dementia in an elderly Asian community cohort

PF Hsu, WH Pan, BS Yip, RCY Chen, HM Cheng… - Journal of the American …, 2017 - Elsevier
Background Many studies have investigated the association between markers for peripheral
inflammation and risk of dementia, but the results have been conflicting. We aimed to …

C‐reactive protein levels and risk of dementia—Observational and genetic studies of 111,242 individuals from the general population

SH Hegazy, JQ Thomassen… - Alzheimer's & …, 2022 - Wiley Online Library
Introduction Increased plasma levels of C‐reactive protein (CRP) in midlife are associated
with increased risk of Alzheimer's disease (AD), whereas in older age the opposite …

High levels of serum C‐reactive protein are associated with greater risk of all‐cause mortality, but not dementia, in the oldest‐old: Results from the 90+ study

BA Kravitz, MM Corrada… - Journal of the American …, 2009 - Wiley Online Library
OBJECTIVES: To evaluate whether high levels of C‐reactive protein (CRP) in serum are
associated with greater risk of all‐cause dementia or mortality in the oldest‐old. DESIGN …

Association of C-reactive protein with mild cognitive impairment

RO Roberts, YE Geda, DS Knopman, BF Boeve… - Alzheimer's & …, 2009 - Elsevier
BACKGROUND: Inflammation is proposed to play a role in the development of Alzheimer's
disease, and may also be involved in the pathogenesis of mild cognitive impairment (MCI) …

C-reactive protein as a predictor of mild cognitive impairment conversion into Alzheimer's disease dementia

A Fernandes, M Tábuas-Pereira, D Duro, M Lima… - Experimental …, 2020 - Elsevier
Background and aims Increasing evidence suggests that inflammation plays an important
role in brain aging and neurodegeneration. Pathological studies demonstrate the presence …

Decreased C-reactive protein levels in Alzheimer disease

SE O'Bryant, SC Waring, V Hobson… - Journal of geriatric …, 2010 - journals.sagepub.com
C-reactive protein (CRP) is an acute-phase reactant that has been found to be associated
with Alzheimer disease (AD) in histopathological and longitudinal studies; however, little …