Adaptive metabolic and inflammatory responses identified using accelerated aging metrics are linked to adverse outcomes in severe SARS-CoV-2 infection
A Márquez-Salinas, CA Fermín-Martínez… - The Journals of …, 2021 - academic.oup.com
Background Chronological age (CA) is a predictor of adverse coronavirus disease 2019
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
Increased pace of aging in COVID-related mortality
Identifying prognostic biomarkers and risk stratification for COVID-19 patients is a
challenging necessity. One of the core survival factors is patient age. However …
challenging necessity. One of the core survival factors is patient age. However …
Biological aging predicts vulnerability to COVID-19 severity in UK Biobank participants
Background Age and disease prevalence are the 2 biggest risk factors for Coronavirus
disease 2019 (COVID-19) symptom severity and death. We therefore hypothesized that …
disease 2019 (COVID-19) symptom severity and death. We therefore hypothesized that …
[HTML][HTML] COVID-19 severity is predicted by earlier evidence of accelerated aging
With no known treatments or vaccine, COVID-19 presents a major threat, particularly to older
adults, who account for the majority of severe illness and deaths. The age-related …
adults, who account for the majority of severe illness and deaths. The age-related …
Accelerated ageing is associated with increased COVID-19 severity and differences across ethnic groups may exist
J Reeves, JS Kooner, W Zhang - Frontiers in Public Health, 2022 - frontiersin.org
Background While increased age is an established risk factor for COVID-19, there is great
heterogeneity in outcomes within age groups. This is because chronological age does not …
heterogeneity in outcomes within age groups. This is because chronological age does not …
[HTML][HTML] Physiological health indexes predict deterioration and mortality in patients with COVID-19: a comparative study
I Strazhesko, O Tkacheva, D Kashtanova… - Aging (Albany …, 2022 - ncbi.nlm.nih.gov
Old age is a crucial risk factor for severe coronavirus disease 2019 (COVID-19), with serious
or fatal outcomes disproportionately affecting older adults compared with the rest of the …
or fatal outcomes disproportionately affecting older adults compared with the rest of the …
Biomarkers of ageing and frailty may predict COVID-19 severity
KJ Wanhella, C Fernandez-Patron - Ageing research reviews, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is caused by the novel coronavirus, Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: considerations beyond chronological …
OY Bello-Chavolla, A González-Díaz… - The Journals of …, 2021 - academic.oup.com
Background COVID-19 has had a disproportionate impact on older adults. Mexico's
population is younger, yet COVID-19's impact on older adults is comparable to countries …
population is younger, yet COVID-19's impact on older adults is comparable to countries …
Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors
M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …
Age-related changes in plasma biomarkers and their association with mortality in COVID-19
EHA Michels, B Appelman… - European …, 2023 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly
in older patients. Several immunomodulating therapies seem less beneficial in these …
in older patients. Several immunomodulating therapies seem less beneficial in these …