Deep learning-based multifeature integration robustly predicts central lymph node metastasis in papillary thyroid cancer

Z Wang, L Qu, Q Chen, Y Zhou, H Duan, B Li, Y Weng… - BMC cancer, 2023 - Springer
Background Few highly accurate tests can diagnose central lymph node metastasis (CLNM)
of papillary thyroid cancer (PTC). Genetic sequencing of tumor tissue has allowed the …

OGDHL closely associates with tumor microenvironment and can serve as a prognostic biomarker for papillary thyroid cancer

M Mao, R Huang, J Zheng, H Liang, W Huang… - Cancer …, 2021 - Wiley Online Library
Background Papillary thyroid cancer (PTC) is the most common type of thyroid cancer.
However, due to the lack of reliable prognostic biomarkers for PTC, overtreatment has been …

[HTML][HTML] Identification of novel diagnostic biomarkers for thyroid carcinoma

X Wang, Q Zhang, Z Cai, Y Dai, L Mou - Oncotarget, 2017 - ncbi.nlm.nih.gov
Thyroid carcinoma (THCA) is the most universal endocrine malignancy worldwide.
Unfortunately, a limited number of large-scale analyses have been performed to identify …

Identification and validation of a prognostic anoikis-related gene signature in papillary thyroid carcinoma by integrated analysis of single-cell and bulk RNA …

K Zheng, XX Zhang, X Yu, B Yu, YF Yang - Medicine, 2024 - journals.lww.com
Papillary thyroid carcinoma (PTC) prognosis may be deteriorated due to the metastases,
and anoikis palys an essential role in the tumor metastasis. However, the potential effect of …

Integrated analysis of tumor microenvironment features to establish a diagnostic model for papillary thyroid cancer using bulk and single-cell RNA sequencing …

Y Wang, W Song, Y Li, Z Liu, K Zhao, L Jia… - Journal of Cancer …, 2023 - Springer
Background Characterizing tumor microenvironment using single-cell RNA sequencing has
been a promising strategy for cancer diagnosis and treatment. However, a few studies have …

Prognostic prediction of patients having classical papillary thyroid carcinoma with a 4 mRNA-based risk model

L Xiang, JH Zhao, Y Tang, JW Tan, LB Li, C Gong - Medicine, 2024 - journals.lww.com
The dysregulation of protein-coding genes involved in various biological functions is closely
associated with the progression of thyroid cancer. This study aimed to investigate the effects …

Correlations of lncRNAs with cervical lymph node metastasis and prognosis of papillary thyroid carcinoma

N Li, M Cui, P Yu, Q Li - OncoTargets and therapy, 2019 - Taylor & Francis
Background Cervical lymph node metastasis is an important prognostic indicator for
papillary thyroid carcinoma (PTC) and affects treatment strategies for PTC. lncRNAs …

Identification of key functional gene signatures indicative of dedifferentiation in papillary thyroid cancer

W Xu, C Li, B Ma, Z Lu, Y Wang, H Jiang, Y Luo… - Frontiers in …, 2021 - frontiersin.org
Background: Differentiated thyroid cancer (DTC) is the most common type of thyroid cancer.
Many of them can relapse to dedifferentiated thyroid cancer (DDTC) and exhibit different …

Prediction of TNFRSF9 expression and molecular pathological features in thyroid cancer using machine learning to construct Pathomics models

Y Liu, J Zhang, S Li, W Chen, R Wu, Z Hao, J Xu - Endocrine, 2024 - Springer
Background The TNFRSF9 molecule is pivotal in thyroid carcinoma (THCA) development.
This study utilizes Pathomics techniques to predict TNFRSF9 expression in THCA tissue and …

Integrated bioinformatics analysis for the identification of key genes and signaling pathways in thyroid carcinoma

B Zhang, Z Chen, Y Wang… - Experimental and …, 2021 - spandidos-publications.com
Thyroid carcinoma (TC) is one of the most common types of endocrine neoplasm with poor
prognosis due to its aggressive behavior. Biomarkers for early diagnosis and prevention of …