Association of unhealthy lifestyle and childhood adversity with acceleration of aging among UK biobank participants

G Yang, X Cao, X Li, J Zhang, C Ma, N Zhang… - JAMA network …, 2022 - jamanetwork.com
Importance Accelerated aging makes adults more vulnerable to chronic diseases and death.
Whether childhood adversity is associated with accelerated aging processes, and to what …

Association of early-life adversity with measures of accelerated biological aging among children in China

Y Sun, J Fang, Y Wan, P Su, F Tao - JAMA Network Open, 2020 - jamanetwork.com
Importance A growing body of literature suggests that exposure to early-life adversity (ELA)
is associated with accelerated biological aging, offering 1 mechanism through which ELA …

Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality

X Li, X Cao, J Zhang, J Fu… - Journal of the …, 2024 - Wiley Online Library
Background With two well‐validated aging measures capturing mortality and morbidity risk,
this study examined whether and to what extent aging mediates the associations of …

Dimensions of childhood adversity differentially affect biological aging in major depression

R Rampersaud, E Protsenko, R Yang, V Reus… - Translational …, 2022 - nature.com
Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …

[HTML][HTML] Associations between exposure to adverse childhood experiences and biological aging: evidence from the Canadian Longitudinal Study on Aging

O Mian, DW Belsky, AA Cohen, LN Anderson… - …, 2022 - Elsevier
People exposed to adverse childhood experiences (ACEs) suffer from an increased risk of
chronic disease and shorter lifespan. These individuals also tend to exhibit accelerated …

Childhood adversity: a gateway to multimorbidity in older age?

Y Henchoz, L Seematter-Bagnoud, D Nanchen… - Archives of gerontology …, 2019 - Elsevier
Background Multimorbidity, or co-occurrence of several chronic diseases, has major
consequences in terms of function, quality of life and mortality. Recent advances suggest …

Social engagement and allostatic load mediate between adverse childhood experiences and multimorbidity in mid to late adulthood: the Canadian Longitudinal Study …

L Atkinson, D Joshi, P Raina, LE Griffith… - Psychological …, 2023 - cambridge.org
Background Adverse childhood experiences (ACEs) are associated with multimorbidity in
adulthood. This link may be mediated by psychosocial and biological factors, but evidence is …

Association of history of psychopathology with accelerated aging at midlife

J Wertz, A Caspi, A Ambler, J Broadbent… - JAMA …, 2021 - jamanetwork.com
Importance Individuals with mental disorders are at an elevated risk of developing chronic
age-related physical diseases. However, it is not clear whether psychopathology is also …

Early life adversity and adult biological risk profiles

EM Friedman, AS Karlamangla… - Psychosomatic …, 2015 - journals.lww.com
Objectives To determine whether there is a relationship between early life adversity (ELA)
and biological parameters known to predict health risks and to examine the extent to which …

Childhood adversity and adult health: The role of developmental timing and associations with accelerated aging

MME Riem, A Karreman - Child maltreatment, 2019 - journals.sagepub.com
Childhood adversity has been associated with poor adult health. However, it is unclear
whether timing of adversity matters in this association and whether adversity is related to …