Early life adversity, pubertal timing, and epigenetic age acceleration in adulthood

EJ Hamlat, AA Prather, S Horvath… - Developmental …, 2021 - Wiley Online Library
Background Given associations linking early life adversity, pubertal timing, and biological
aging, we examined the direct and indirect effects of early life trauma on adult biological …

Biological aging in childhood and adolescence following experiences of threat and deprivation: A systematic review and meta-analysis.

NL Colich, ML Rosen, ES Williams… - Psychological …, 2020 - psycnet.apa.org
Life history theory argues that exposure to early life adversity (ELA) accelerates
development, although existing evidence for this varies. We present a meta-analysis and …

[HTML][HTML] Dimensions of childhood adversity differentially affect biological aging in major depression

R Rampersaud, E Protsenko, R Yang, V Reus… - Translational …, 2022 - nature.com
Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …

Early experiences of threat, but not deprivation, are associated with accelerated biological aging in children and adolescents

JA Sumner, NL Colich, M Uddin, D Armstrong… - Biological …, 2019 - Elsevier
Background Recent conceptual models argue that early life adversity (ELA) accelerates
development, which may contribute to poor mental and physical health outcomes. Evidence …

The association between adverse childhood experiences and epigenetic age acceleration in the Canadian longitudinal study on aging (CLSA)

D Joshi, A Gonzalez, D Lin, P Raina - Aging Cell, 2023 - Wiley Online Library
Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …

Stressful life events and accelerated biological aging over time in youths

JA Sumner, X Gao, S Gambazza, CK Dye… - …, 2023 - Elsevier
Experiencing adversity in childhood and adolescence, including stressful life events (SLEs),
may accelerate the pace of development, leading to adverse mental and physical health …

[HTML][HTML] Epigenetic age acceleration as a biomarker for impaired cognitive abilities in adulthood following early life adversity and psychiatric disorders

JM Felt, N Yusupov, KD Harrington, J Fietz… - Neurobiology of …, 2023 - Elsevier
Background Early life adversity and psychiatric disorders are associated with earlier
declines in neurocognitive abilities during adulthood. These declines may be preceded by …

The impact of psychosocial stress from life trauma and racial discrimination on epigenetic aging—a systematic review

S Lim, D Nzegwu, ML Wright - Biological Research for …, 2022 - journals.sagepub.com
Purpose The purpose of this review was to explore the effects of psychosocial stress from life
trauma and racial discrimination on epigenetic aging. Design A systematic review of the last …

Early-life adversity accelerates child and adolescent development

J Belsky - Current Directions in Psychological Science, 2019 - journals.sagepub.com
Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

[HTML][HTML] The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents

A Suarez, J Lahti, D Czamara, M Lahti-Pulkkinen… - Clinical …, 2018 - Springer
Background Molecular aging biomarkers, such as epigenetic age predictors, predict risk
factors of premature aging, and morbidity/mortality more accurately than chronological age …