Background Longitudinal studies are needed to clarify whether early adversities are
associated with advanced methylation age or if they actually accelerate methylation aging …

Importance A growing body of literature suggests that exposure to early-life adversity (ELA)
is associated with accelerated biological aging, offering 1 mechanism through which ELA …

Child maltreatment is a major risk factor for both depressive and anxiety disorders. However,
many children exposed to maltreatment never meet diagnostic threshold for either disorder …

Accelerated epigenetic aging relative to chronological age has been found to be associated
with higher risk of mortality in adults. However, little is known about whether and how in …

Exposure to early-life adversity (ELA) is associated with elevated risk for depression and
anxiety disorders in adolescence. Identifying mechanisms through which ELA contributes to …

Emerging research suggests associations of physical and psychosocial stressors with
epigenetic aging. Although this work has included early-life exposures, data on maternal …

Background Higher mortality experienced by socially disadvantaged groups and/or
racial/ethnic minorities is hypothesized to be, at least in part, due to an acceleration of the …

Objectives Exposure to adversity has been linked to accelerated biological aging, which in
turn has been shown to predict numerous physical and mental health problems. In recent …

Background Earlier age of pubertal maturation in females is associated with increased risk
for mental health problems in adolescence, compared with on-time or later maturation …

BackgroundEarly pubertal timing in girls is associated with elevated risk for dieting and
eating pathology. The relative importance of biological versus socio-environmental …