Y Zong, Y Lin, T Wei, Q Cheng - Advanced Materials, 2023 - Wiley Online Library
Messenger RNA (mRNA) has received great attention in the prevention and treatment of various diseases due to the success of coronavirus disease 2019 (COVID‐19) mRNA …
Messenger RNA (mRNA) is now in the limelight as a powerful tool for treating various human diseases, especially malignant tumors, thanks to the remarkable clinical outcomes of …
Cancer immunotherapy, which harnesses the power of the immune system, has shown immense promise in the fight against malignancies. Messenger RNA (mRNA) stands as a …
ML Guevara, F Persano, S Persano - Frontiers in chemistry, 2020 - frontiersin.org
Over the past decade, messenger RNA (mRNA) has emerged as potent and flexible platform for the development of novel effective cancer immunotherapies. Advances in non-viral gene …
T Huang, L Peng, Y Han, D Wang, X He… - Frontiers in …, 2022 - frontiersin.org
Messenger RNA (mRNA) vaccines constitute an emerging therapeutic method with the advantages of high safety and efficiency as well as easy synthesis; thus, they have been …
P Karmacharya, BR Patil, JO Kim - Journal of pharmaceutical investigation, 2022 - Springer
Background Cancer remains a serious health concern worldwide, and different approaches are being developed for its treatment. The strategy to use the immune system as an …
EJ Sayour, A Grippin, G De Leon, B Stover… - Nano …, 2018 - ACS Publications
Translation of nanoparticles (NPs) into human clinical trials for patients with refractory cancers has lagged due to unknown biologic reactivities of novel NP designs. To overcome …
Y Granot, D Peer - Seminars in immunology, 2017 - Elsevier
Abstract mRNA molecules hold tremendous potential as a tool for gene therapy of a wide range of diseases. However, the main hurdle in implementation of mRNA for therapeutics …
X Xu, T Xia - ACS Nanoscience Au, 2023 - ACS Publications
The success of mRNA vaccines during the COVID-19 pandemic has greatly accelerated the development of mRNA therapy. mRNA is a negatively charged nucleic acid that serves as a …