[HTML][HTML] ACE2 and COVID-19 Susceptibility and Severity

M Zheng - Aging and disease, 2022 - ncbi.nlm.nih.gov
Sick, male, and older populations are more vulnerable to COVID-19. However, it remains
unclear whether a common mechanism exists across different demographic characteristics …

Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of SARS-CoV-2: a Mendelian randomization analysis …

S Rao, A Lau, HC So - Diabetes care, 2020 - Am Diabetes Assoc
OBJECTIVE COVID-19 has become a major public health problem. There is good evidence
that ACE2 is a receptor for SARS-CoV-2, and high expression of ACE2 may increase …

ACE2 polymorphisms as potential players in COVID-19 outcome

AS Khayat, PP de Assumpção, BC Meireles Khayat… - PLoS …, 2020 - journals.plos.org
The clinical condition COVID-19, caused by SARS-CoV-2, was declared a pandemic by the
WHO in March 2020. Currently, there are more than 5 million cases worldwide, and the …

[HTML][HTML] High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

H Xu, L Zhong, J Deng, J Peng, H Dan… - International journal of …, 2020 - nature.com
It has been reported that ACE2 is the main host cell receptor of 2019-nCoV and plays a
crucial role in the entry of virus into the cell to cause the final infection. To investigate the …

Increasing host cellular receptor—angiotensin‐converting enzyme 2 expression by coronavirus may facilitate 2019‐nCoV (or SARS‐CoV‐2) infection

MW Zhuang, Y Cheng, J Zhang… - Journal of medical …, 2020 - Wiley Online Library
The ongoing outbreak of a new coronavirus (2019‐nCoV, or severe acute respiratory
syndrome coronavirus 2 [SARS‐CoV‐2]) has caused an epidemic of the acute respiratory …

[HTML][HTML] Role of genetic variants and gene expression in the susceptibility and severity of COVID-19

S Choudhary, K Sreenivasulu, P Mitra… - Annals of laboratory …, 2021 - synapse.koreamed.org
Since its first report in December 2019, coronavirus disease 2019 (COVID-19), caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has rapidly emerged as a …

Investigation of the genetic variation in ACE2 on the structural recognition by the novel coronavirus (SARS-CoV-2)

X Guo, Z Chen, Y Xia, W Lin, H Li - Journal of Translational Medicine, 2020 - Springer
Background The outbreak of coronavirus disease (COVID-19) was caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), through its surface spike glycoprotein (S …

Variants in ACE2; potential influences on virus infection and COVID-19 severity

B Bakhshandeh, SG Sorboni, AR Javanmard… - Infection, Genetics and …, 2021 - Elsevier
The third pandemic of coronavirus infection, called COVID-19 disease, was first detected in
November 2019th. Various determinants of disease progression such as age, sex, virus …

Polymorphisms of ACE (I/D) and ACE2 receptor gene (Rs2106809, Rs2285666) are not related to the clinical course of COVID‐19: A case study

S Karakaş Çelik, G Çakmak Genç… - Journal of Medical …, 2021 - Wiley Online Library
Coronavirus disease 2019 (COVID‐19) is an infectious disease, and the reason behind the
currently ongoing pandemic, caused by severe acute respiratory syndrome coronavirus 2 …

Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2

K Sun, L Gu, L Ma, Y Duan - Heliyon, 2021 - cell.com
Abstract The recent pandemic, COVID-19, is caused by a novel coronavirus, SARS-CoV-2,
with elusive origin. SARS-CoV-2 infects mammalian cells via ACE2, a transmembrane …