[HTML][HTML] The role of molecular subtypes and immune infiltration characteristics based on disulfidptosis-associated genes in lung adenocarcinoma

C Qi, J Ma, J Sun, X Wu, J Ding - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Lung adenocarcinoma (LUAD) is the most common type of lung cancer which accounts for
about 40% of all lung cancers. Early detection, risk stratification and treatment are important …

Multi‐omics analysis of disulfidptosis regulators and therapeutic potential reveals glycogen synthase 1 as a disulfidptosis triggering target for triple‐negative breast …

J Xie, X Deng, Y Xie, H Zhu, P Liu, W Deng, L Ning… - MedComm, 2024 - Wiley Online Library
Disruption of disulfide homeostasis during biological processes can have fatal
consequences. Excess disulfides induce cell death in a novel manner, termed as …

[HTML][HTML] Molecular landmarks of tumor disulfidptosis across cancer types to promote disulfidptosis-target therapy

D Zhao, Y Meng, Y Dian, Q Zhou, Y Sun, J Le, F Zeng… - Redox Biology, 2023 - Elsevier
The mystery about the mechanistic basis of disulfidptosis has recently been unraveled and
shows promise as an effective treatment modality for triggering cancer cell death. However …

Establishment of a prognostic risk prediction model incorporating disulfidptosis-related lncRNA for patients with prostate cancer

Y Mulati, C Lai, J Luo, J Hu, X Xu, D Kong, Y Xiao… - BMC cancer, 2024 - Springer
Abstract Purpose Prostate cancer (PCa) is one of the major tumor diseases that threaten
men's health globally, and biochemical recurrence significantly impacts its prognosis …

A novel disulfidptosis and glycolysis related risk score signature for prediction of prognosis and ICI therapeutic responsiveness in colorectal cancer

J Li, C Yang, Y Zheng - Scientific Reports, 2023 - nature.com
Disulfidptosis is a newly-identified non-programmed cell death mode with tight associations
with glucose metabolism. Elevated glycolysis is an important metabolic feature of tumor …

A novel disulfidptosis-associated expression pattern in breast cancer based on machine learning

Z Wang, X Du, W Lian, J Chen, C Hong, L Li… - Frontiers in …, 2023 - frontiersin.org
Background: Breast cancer (BC), the leading cause of cancer-related deaths among women,
remains a serious threat to human health worldwide. The biological function and prognostic …

Elaboration and validation of a prognostic signature associated with disulfidoptosis in lung adenocarcinoma, consolidated with integration of single-cell RNA …

D He, H Tang, X Yang, X Liu, Y Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD), the predominant subtype of non-small cell lung
cancer (NSCLC), remains a pervasive global public health concern. Disulfidoptosis, a …

Integrated single-cell and bulk RNA sequencing in pancreatic cancer identifies disulfidptosis-associated molecular subtypes and prognostic signature

Y Wu, J Shang, Q Ruan, X Tan - Scientific Reports, 2023 - nature.com
Pancreatic cancer (PC) is known for its high degree of heterogeneity and exceptionally
adverse outcome. While disulfidptosis is the most recently identified form of cell death, the …

Disulfidptosis-associated long non-coding RNA signature predicts the prognosis, tumor microenvironment, and immunotherapy and chemotherapy options in colon …

W Xue, K Qiu, B Dong, D Guo, J Fu, C Zhu… - Cancer Cell …, 2023 - Springer
Background Disulfidptosis is independent of apoptosis, ferroptosis, and cuproptosis and is
associated with cancer progression, treatment response, and prognosis. However, the …

A demonstration based on multi-omics transcriptome sequencing data revealed disulfidptosis heterogeneity within the tumor microenvironment of esophageal …

F Liu, D Yuan, X Liu, S Zhuo, X Liu, H Sheng, M Sha… - Discover Oncology, 2023 - Springer
Background It is of great concern to identify prognostic signatures for the prediction and
prediction of esophageal squamous cell carcinoma (ESCC), which is the lethal pathological …