Background Development of in vivo biomarkers has shifted the diagnosis of Alzheimer's
disease (AD) from the later dementia stages of disease towards the earlier stages and has …

Introduction: Alzheimer's disease (AD) is the most common cause of dementia globally and
imposes a growing burden on healthcare systems. Historical background: Alois Alzheimer …

Alzheimer's disease (AD) is a heterogeneous disease and exhibits diverse clinical
presentations and disease progression. Some pathological and anatomical subtypes have …

Background Given the complex and progressive nature of Alzheimer's disease (AD), a
precision medicine approach for diagnosis and treatment requires the identification of …

Alzheimer's disease (AD) is the most common and most studied cause of dementia.
Significant advances have been made since the first set of clinical criteria for AD were put …

Background Alzheimer's disease (AD) is a neurodegenerative disorder with significant
heterogeneity. Different AD phenotypes may be associated with specific brain network …

Since the earliest descriptions of Alzheimer's disease (AD), many theories have been
advanced as to its cause. These include:(1) exacerbation of aging,(2) degeneration of …

Abstract Background The NIA-AA research framework proposes a biological definition of
Alzheimer's disease, where asymptomatic persons with amyloid deposition would be …

Alzheimer's disease is the most common form of dementia and the most common
neurodegenerative disease. It manifests as a decline in short-term memory and cognition …

Individuals with intact cognition and neuropathology consistent with Alzheimer's disease
(AD) are referred to as asymptomatic AD (AsymAD). These individuals are highly likely to …