Why do men have worse COVID-19-related outcomes? A systematic review and meta-analysis with sex adjusted for age

J Fabião, B Sassi, EF Pedrollo, F Gerchman… - Brazilian Journal of …, 2022 - SciELO Brasil
We aimed to study the mechanism behind worse coronavirus disease-19 (COVID-19)
outcomes in men and whether the differences between sexes regarding mortality as well as …

[PDF][PDF] Coronavirus COV-19/SARS-CoV-2 affects women less than men: clinical response to viral infection

P Conti, A Younes - J Biol Regul Homeost Agents, 2020 - researchgate.net
340 treated with estrogen respond better to the antigen and express Toll-like 7 (TLR7) with
greater efficiency. CoV-19 binds to TLRs (key molecules in triggering innate immunity) of …

Evidence of gender differences in the diagnosis and management of coronavirus disease 2019 patients: an analysis of electronic health records using natural …

J Ancochea, JL Izquierdo… - Journal of Women's …, 2021 - liebertpub.com
Background: The impact of sex and gender in the incidence and severity of coronavirus
disease 2019 (COVID-19) remains controversial. Here, we aim to describe the …

Sex-differences in COVID-19 diagnosis, risk factors and disease comorbidities: A large US-based cohort study

SA Kharroubi, M Diab-El-Harake - Frontiers in public health, 2022 - frontiersin.org
Introduction Morbidity and mortality from COVID-19 are higher among men, however,
underlying pathways remain controversial. We aim to investigate sex-gender differences in …

Influence of age and gender on the epidemic of COVID-19: Evidence from 177 countries and territories—an exploratory, ecological study

D Hu, X Lou, N Meng, Z Li, Y Teng, Y Zou… - Wiener Klinische …, 2021 - Springer
Background The pandemic of coronavirus disease 2019 (COVID-19) is spreading worldwide
with an uncertain ultimate impact on every aspect of human society. Recognizing the groups …

Sex and gender differences in COVID-19: an Italian local register-based study

F Fortunato, D Martinelli, SL Caputo, T Santantonio… - BMJ open, 2021 - bmjopen.bmj.com
Objectives The present study aimed to explore differences in COVID-19 outcomes between
male and female cases in the Apulian District of Foggia, Italy. Design and setting We …

Gendered effects on inflammation reaction and outcome of COVID‐19 patients in Wuhan

L Qin, X Li, J Shi, M Yu, K Wang, Y Tao… - Journal of medical …, 2020 - Wiley Online Library
Background The rapid outbreak of coronavirus disease 2019 (COVID‐19) has turned into a
public health emergency of international concern. Epidemiological research has shown that …

Sex, gender and COVID-19: a call to action

SB Ahmed, SM Dumanski - Canadian Journal of Public Health, 2020 - Springer
An understanding of the influence of sex (biological attributes) and gender (socially
constructed roles, behaviours, expressions, identities) factors on the risk of infection …

Are we equal in adversity? Does Covid-19 affect women and men differently?

S Rozenberg, J Vandromme, C Martin - Maturitas, 2020 - Elsevier
Background & objectives This article examines whether women are less prone than men to
Covid-19 infections and their complications. Data sources We reviewed available databases …

Molecular and biological mechanisms underlying gender differences in COVID-19 severity and mortality

Z Wehbe, SH Hammoud, HM Yassine… - Frontiers in …, 2021 - frontiersin.org
Globally, over two million people have perished due to the recent pandemic caused by
SARS-CoV-2. The available epidemiological global data for SARS-CoV-2 portrays a higher …