Background. Chronic inflammation, measured by interleukin-6, predicts incident disability
among elderly people. However, little is known about the relation of C-reactive protein …

Background. Chronic inflammation has been proposed as a biological mechanism
underlying the decline in physical function that occurs with aging. The purpose of this …

Background and objective: C-reactive protein (CRP) is a widely used cardiovascular risk
marker, but questions remain about its role in the disability process in old age. This study …

Background. Some studies have proposed chronic inflammation as an underlying biological
mechanism responsible for physical function decline in elderly people. The aim of this study …

Background Elevated systematic inflammation is a hallmark of aging, but the association of
long-term inflammation trajectories with subsequent aging phenotypes has been little …

Background This cohort of “late middle-aged” African Americans has an excess of disability.
We aimed to determine associations of circulating cytokine receptors (sTNFR1, sTNFR2 …

Background Chronic subclinical inflammation may contribute to impaired physical function in
older adults; however, more data are needed to determine whether inflammation is a …

OBJECTIVES: To determine the effects of a long‐term exercise intervention on two
prominent biomarkers of inflammation (C‐reactive protein (CRP) and interleukin‐6 (IL‐6)) in …

Background. Recent studies have suggested that inflammation may play an important role in
aging and the development of disabilities, but knowledge about its importance in the …

Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …