Linking C-reactive protein to late-life disability in the National Health and Nutrition Examination Survey (NHANES) 1999–2002

HK Kuo, JF Bean, CJ Yen… - The Journals of …, 2006 - academic.oup.com
Background. Chronic inflammation, measured by interleukin-6, predicts incident disability
among elderly people. However, little is known about the relation of C-reactive protein …

Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful …

DR Taaffe, TB Harris, L Ferrucci, J Rowe… - The Journals of …, 2000 - academic.oup.com
Background. Chronic inflammation has been proposed as a biological mechanism
underlying the decline in physical function that occurs with aging. The purpose of this …

Association between C-reactive protein and physical performance in older populations: results from the International Mobility in Aging Study (IMIAS)

ACPA Sousa, MV Zunzunegui, A Li, SP Phillips… - Age and …, 2016 - academic.oup.com
Background and objective: C-reactive protein (CRP) is a widely used cardiovascular risk
marker, but questions remain about its role in the disability process in old age. This study …

Inflammatory markers and physical performance in older persons: the InCHIANTI study

M Cesari, BWJH Penninx, M Pahor… - The Journals of …, 2004 - academic.oup.com
Background. Some studies have proposed chronic inflammation as an underlying biological
mechanism responsible for physical function decline in elderly people. The aim of this study …

Association of 10-year C-reactive protein trajectories with markers of healthy aging: findings from the English longitudinal study of aging

C Lassale, GD Batty, A Steptoe, D Cadar… - The Journals of …, 2019 - academic.oup.com
Background Elevated systematic inflammation is a hallmark of aging, but the association of
long-term inflammation trajectories with subsequent aging phenotypes has been little …

Higher C-reactive protein and soluble tumor necrosis factor receptor levels are associated with poor physical function and disability: a cross-sectional analysis of a …

MT Haren, TK Malmstrom, DK Miller… - … Series A: Biomedical …, 2010 - academic.oup.com
Background This cohort of “late middle-aged” African Americans has an excess of disability.
We aimed to determine associations of circulating cytokine receptors (sTNFR1, sTNFR2 …

Chronic inflammation is associated with low physical function in older adults across multiple comorbidities

TE Brinkley, X Leng, ME Miller… - … Series A: Biomedical …, 2009 - academic.oup.com
Background Chronic subclinical inflammation may contribute to impaired physical function in
older adults; however, more data are needed to determine whether inflammation is a …

Exercise training and plasma C‐reactive protein and interleukin‐6 in elderly people

BJ Nicklas, FC Hsu, TJ Brinkley… - Journal of the …, 2008 - Wiley Online Library
OBJECTIVES: To determine the effects of a long‐term exercise intervention on two
prominent biomarkers of inflammation (C‐reactive protein (CRP) and interleukin‐6 (IL‐6)) in …

Inflammatory markers and physical performance among nonagenarians

K Tiainen, M Hurme, A Hervonen… - … Series A: Biomedical …, 2010 - academic.oup.com
Background. Recent studies have suggested that inflammation may play an important role in
aging and the development of disabilities, but knowledge about its importance in the …

[HTML][HTML] Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

M Puzianowska-Kuźnicka, M Owczarz… - Immunity & …, 2016 - Springer
Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …