Immune response to COVID-19 in older adults

M Jergović, CP Coplen, JL Uhrlaub… - The Journal of Heart and …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the third highly
pathogenic coronavirus to emerge in the human population in last two decades. SARS-CoV …

Aging in COVID-19: Vulnerability, immunity and intervention

Y Chen, SL Klein, BT Garibaldi, H Li, C Wu… - Ageing research …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …

Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

Covid-19 and immunity in aging populations—a new research agenda

WC Koff, MA Williams - New England Journal of Medicine, 2020 - Mass Medical Soc
Covid-19 and Immunity in Aging Populations As billions of dollars flow into research and
development efforts aimed at controlling SARS-CoV-2, the pandemic response remains …

COVID-19 and crosstalk with the hallmarks of aging

S Salimi, JM Hamlyn - The Journals of Gerontology: Series A, 2020 - academic.oup.com
Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …

Remodeling of the immune response with aging: immunosenescence and its potential impact on COVID-19 immune response

LL Cunha, SF Perazzio, J Azzi, P Cravedi… - Frontiers in …, 2020 - frontiersin.org
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

Immunosenescence and inflamm-ageing in COVID-19

MR Zinatizadeh, PK Zarandi, M Ghiasi… - Ageing Research …, 2023 - Elsevier
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

Aged population and immunocompromised patients: impact on SARS-CoV-2 variants and treatment outcomes

VP Chavda, MT Chhabria, V Apostolopoulos - Biologics, 2022 - mdpi.com
Patients with an immunocompromised state are at risk of developing a long-term infection
from the coronavirus 2 that causes severe acute respiratory syndrome (SARS-CoV-2). It has …

COVID-19 and elderly: beyond the respiratory drama

A Sciacqua, R Pujia, F Arturi, ML Hribal… - Internal and Emergency …, 2020 - Springer
Within a very short period, Italy was hit by an urgent health crisis followed by a relentless
number of deaths. State health officials and policy makers have been making extraordinary …