Integrated microRNA, gene expression and transcription factors signature in papillary thyroid cancer with lymph node metastasis

NS Ab Mutalib, SN Othman, AM Yusof, SNA Suhaimi… - PeerJ, 2016 - peerj.com
Background. Papillary thyroid carcinoma (PTC) is the commonest thyroid malignancy
originating from the follicle cells in the thyroid. Despite a good overall prognosis, certain high …

Deep learning-based multifeature integration robustly predicts central lymph node metastasis in papillary thyroid cancer

Z Wang, L Qu, Q Chen, Y Zhou, H Duan, B Li, Y Weng… - BMC cancer, 2023 - Springer
Background Few highly accurate tests can diagnose central lymph node metastasis (CLNM)
of papillary thyroid cancer (PTC). Genetic sequencing of tumor tissue has allowed the …

Identification of the EMT-related genes signature for predicting occurrence and progression in thyroid cancer

Q Li, S Jiang, T Feng, T Zhu, B Qian - OncoTargets and therapy, 2021 - Taylor & Francis
Background The detection rate of thyroid cancer (TC) has been continuously improved due
to the development of detection technology. Epithelial–mesenchymal transition (EMT) is …

Identification of hub genes in papillary thyroid carcinoma: robust rank aggregation and weighted gene co-expression network analysis

Y Liu, TY Chen, ZY Yang, W Fang, Q Wu… - Journal of translational …, 2020 - Springer
Background Papillary thyroid carcinoma (PTC), which is the most common endocrine
malignancy, has been steadily increasing worldwide in incidence over the years, while …

Single-cell and bulk RNA sequencing reveal heterogeneity and diagnostic markers in papillary thyroid carcinoma lymph-node metastasis

DN Lu, WC Zhang, YZ Lin, HY Jiang, R He… - Journal of …, 2024 - Springer
Purpose Papillary thyroid carcinoma (PTC) is characterized by lymph-node metastasis
(LNM), which affects recurrence and prognosis. This study analyzed PTC LNM by single-cell …

A network-based approach to identify molecular signatures and comorbidities of thyroid cancer

M Ali Hossain, TA Asa, F Huq, JMW Quinn… - … of International Joint …, 2020 - Springer
The molecular mechanisms driving thyroid cancer (TC) development and progression are
poorly understood, but identifying molecular pathways and hub genes abnormally active in …

Identification and validation of potential target genes in papillary thyroid cancer

K Zhang, J Liu, C Li, X Peng, H Li, Z Li - European journal of pharmacology, 2019 - Elsevier
Thyroid cancer (TC) is one of the most common endocrine malignancies, and the incidence
of TC has almost tripled over the past three decades. This increase may partially own to …

[HTML][HTML] Identification of a six gene prognosis signature for papillary thyroid cancer using multi-omics methods and bioinformatics analysis

H Ren, X Liu, F Li, X He, N Zhao - Frontiers in Oncology, 2021 - frontiersin.org
Papillary thyroid carcinoma (PTC) is the most common subtype of thyroid cancer. PTC is
typically curable with an excellent survival rate; however, some patients experience disease …

Integrated bioinformatics analysis of hub genes and pathways in anaplastic thyroid carcinomas

X Gao, J Wang, S Zhang - International journal of …, 2019 - Wiley Online Library
Anaplastic thyroid carcinoma (ATC) is a very rare malignancy; the pathogenesis of which is
still not fully understood. The aim of the present study was to identify hub genes and …

Identification of potential biomarkers for thyroid cancer using bioinformatics strategy: a study based on GEO datasets

Y Shen, S Dong, J Liu, L Zhang, J Zhang… - BioMed research …, 2020 - Wiley Online Library
Background. The molecular mechanisms and genetic markers of thyroid cancer are unclear.
In this study, we used bioinformatics to screen for key genes and pathways associated with …