Aging is the single most important risk factor for diseases that are currently the leading
causes of morbidity and mortality. However, there is considerable inter-individual variability …

Life stress has been associated with accelerated cellular aging and increased risk for
developing aging-related diseases; however, the underlying molecular mechanisms remain …

Psychosocial stress—especially when chronic, excessive, or occurring early in life—has
been associated with accelerated aging and increased disease risk. With rapid aging of the …

Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …

Background Chronic psychological stress is associated with accelerated aging and
increased risk for aging-related diseases, but the underlying molecular mechanisms are …

Adverse effects of psychological stress on physical and mental health, especially in older
age, are well documented. How perceived stress relates to the epigenetic clock measure …

The aging phenotype is the result of a complex interaction between genetic, epigenetic and
environmental factors. Evidence suggests that epigenetic changes (ie, a set of reversible …

Differences in health status by socioeconomic position (SEP) tend to be more evident at
older ages, suggesting the involvement of a biological mechanism responsive to the …

Individuals with psychiatric disorders are at increased risk of age-related diseases and early
mortality. Recent studies demonstrate that this link between mental health and aging is …

Aging is arguably the most familiar yet least-well understood aspect of human biology. The
role of epigenetics in aging and age-related diseases has gained interest given recent …