Recent studies have identified biomarkers of chronological age based on DNA methylation
levels. Since active smoking contributes to a wide spectrum of aging-related diseases in …

Background Individuals of the same chronological age display different rates of biological
ageing. A number of measures of biological age have been proposed which harness age …

The biological markers of aging used to predict physical health status in older people are of
great interest. Telomere shortening, which occurs during the process of cell replication, was …

DNA-methylation (DNAm) levels at age-associated CpG sites can be combined into
epigenetic aging signatures to estimate donor age. It has been demonstrated that the …

Identifying and validating molecular targets of interventions that extend the human health
span and lifespan has been difficult, as most clinical biomarkers are not sufficiently …

Background DNA methylation levels change with age. Recent studies have identified
biomarkers of chronological age based on DNA methylation levels. It is not yet known …

Measures of biological age based on blood DNA methylation, referred to as age
acceleration (AA), have been developed. We examined whether AA was associated with …

DNA methylation (DNAm) algorithms of biological age provide a robust estimate of an
individual's chronological age and can predict their risk of age-related disease and mortality …

DNA methylation age (DNAm age;“epigenetic clock”) has recently been described as highly
correlated with chronological age. Several studies suggest that DNAm age reflects, at least …

DNA methylation (DNAm) has been found to show robust and widespread age-related
changes across the genome. DNAm profiles from whole blood can be used to predict human …