DNA methylation age and physical and cognitive aging
J Maddock, J Castillo-Fernandez… - The Journals of …, 2020 - academic.oup.com
Background DNA methylation (DNAm) age acceleration (AgeAccel) has been shown to be
predictive of all-cause mortality but it is unclear what functional aspect (s) of aging it …
predictive of all-cause mortality but it is unclear what functional aspect (s) of aging it …
“GrimAge,” an epigenetic predictor of mortality, is accelerated in major depressive disorder
Major depressive disorder (MDD) is associated with premature mortality and is an
independent risk factor for a broad range of diseases, especially those associated with …
independent risk factor for a broad range of diseases, especially those associated with …
[HTML][HTML] A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge
Methods to quantify biological aging are emerging as new measurement tools for
epidemiology and population science and have been proposed as surrogate measures for …
epidemiology and population science and have been proposed as surrogate measures for …
Prenatal and early life influences on epigenetic age in children: a study of mother–offspring pairs from two cohort studies
DNA methylation-based biomarkers of aging are highly correlated with actual age.
Departures of methylation-estimated age from actual age can be used to define epigenetic …
Departures of methylation-estimated age from actual age can be used to define epigenetic …
The trajectory of the blood DNA methylome ageing rate is largely set before adulthood: evidence from two longitudinal studies
L Kananen, S Marttila, T Nevalainen, L Kummola… - Age, 2016 - Springer
The epigenetic clock, defined as the DNA methylome age (DNAmAge), is a candidate
biomarker of ageing. In this study, we aimed to characterize the behaviour of this marker …
biomarker of ageing. In this study, we aimed to characterize the behaviour of this marker …
DNA methylation‐based biomarkers of aging were slowed down in a two‐year diet and physical activity intervention trial: the DAMA study
Several biomarkers of healthy aging have been proposed in recent years, including the
epigenetic clocks, based on DNA methylation (DNAm) measures, which are getting …
epigenetic clocks, based on DNA methylation (DNAm) measures, which are getting …
Alcohol consumption and methylation-based measures of biological age
JK Kresovich, AM Martinez Lopez… - The Journals of …, 2021 - academic.oup.com
Epigenetic age acceleration is considered a measure of biological aging based on genome-
wide patterns of DNA methylation. Although age acceleration has been associated with the …
wide patterns of DNA methylation. Although age acceleration has been associated with the …
A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD
DNA methylation patterns at specific cytosine-phosphate-guanine (CpG) sites predictably
change with age and can be used to derive “epigenetic age”, an indicator of biological age …
change with age and can be used to derive “epigenetic age”, an indicator of biological age …
[HTML][HTML] Higher diet quality relates to decelerated epigenetic aging
Background DNA methylation–based epigenetic age measures have been used as
biological aging markers and are associated with a healthy lifespan. Few population-based …
biological aging markers and are associated with a healthy lifespan. Few population-based …
GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality
The aging process is characterized by the presence of high interindividual variation between
individuals of the same chronical age prompting a search for biomarkers that capture this …
individuals of the same chronical age prompting a search for biomarkers that capture this …