Despite increasing research efforts, there is a lack of consensus on defining aging or health.
To understand the underlying processes, and to foster the development of targeted …

Although studies over the last decades have firmly connected a number of genes and
molecular pathways to aging, the aging process as a whole still remains poorly understood …

The world has witnessed a steady rise in both non-infectious and infectious chronic
diseases, prompting a cross-disciplinary approach to understand and treating disease …

Increasing evidence indicates that chronic inflammation and senescence are the cause of
many severe age-related diseases, with both biological processes highly upregulated …

Organismal aging exhibits wide-ranging hallmarks in divergent cell types across tissues,
organs, and systems. The advancement of single-cell technologies and generation of rich …

The Geroscience aims at a better understanding of the biological processes of aging, to
prevent and/or delay the onset of chronic diseases and disability as well as to reduce the …

Metabolomics is the latest 'omics' technology and systems biology science that allows for
comprehensive profiling of small-molecule metabolites in biological systems at a specific …

Accurately measuring biological age is crucial for improving healthcare for the elderly
population. However, the complexity of aging biology poses challenges in how to robustly …

Leading biologists and clinicians interested in aging convened to discuss biomarkers of
aging. The goals were to come to a consensus, construct an agenda for future research, and …

Ageing is a highly complex process; it involves interactions between numerous biochemical
and cellular mechanisms that affect many tissues in an organism. Although work on the …