Background The distribution of ACE2 and accessory proteases (ANAD17 and CTSL) in
cardiovascular tissue and the host cell receptor binding of severe acute respiratory …

Abstract Angiotensin-converting enzyme 2 (ACE2) and accessory proteases (TMPRSS2 and
CTSL) are needed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

Aims Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) directly binds to
ACE2 (angiotensin-converting enzyme 2) to facilitate cellular entry. Compared with the lung …

Using serial analysis of myocardial gene expression employing endomyocardial biopsy
starting material in a dilated cardiomyopathy cohort, we show that mRNA expression of the …

At least 20% of patients hospitalized with corona-virus disease 2019 (COVID-19) have
evidence of cardiac injury and its presence increases mortality. 1 ACE 2 (angiotensin …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of the
Coronavirus disease-19 (COVID-19) pandemic, utilizes angiotensin-converting enzyme 2 …

Age (> 70 years), case fatality rate (CFR, 10.2%) and coexisting conditions, particularly
cardiovascular disease (CFR, 10.5%) and hypertension (CFR, 6.0%), are independent …

COVID-19 is a global pandemic with high infectivity and pathogenicity, accounting for tens of
thousands of deaths worldwide. Recent studies have found that the pathogen of COVID-19 …

The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, creates an urgent
need for identifying molecular mechanisms that mediate viral entry, propagation, and tissue …

The ongoing pandemic, caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), has wreaked havoc worldwide, infecting over eight million people and killing …