Screening for early‐stage disease is vital for reducing colorectal cancer (CRC)‐related
mortality. Methylation of circulating tumor DNA has been previously used for various types of …

Background Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an
increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has …

Background Early detection of colorectal carcinoma (CRC) would help to identify tumors
when curative treatments are available and beneficial. However, current screening methods …

Background Colorectal cancer is the fourth cause of cancer-related deaths worldwide,
though detection at early stages associates with good prognosis. Thus, there is a clear …

Circulating tumor DNA (ctDNA) has emerged as a useful diagnostic and prognostic
biomarker in many cancers. Here, we conducted a study to investigate the potential use of …

Purpose: DNA methylation alterations have emerged as front-runners in cell-free DNA
(cfDNA) biomarker development. However, much effort to date has focused on single …

Background Targeted methylation sequencing of plasma cell-free DNA (cfDNA) has a
potential to expand liquid biopsies to patients with tumors without detectable oncogenic …

Background Early detection and prognosis prediction of colorectal cancer (CRC) can
significantly reduce CRC-related mortality. Recently, circulating tumour DNA (ctDNA) …

Background There is an increasing demand for accurate biomarkers for early non-invasive
colorectal cancer detection. We employed a genome-scale marker discovery method to …

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Early
detection of CRC can significantly reduce this mortality rate. Unfortunately, recommended …