Aging is often perceived as a degenerative process resulting from random accrual of cellular
damage over time. Despite this, age can be accurately estimated by epigenetic clocks based …

In mammals, females generally live longer than males. Nevertheless, the mechanisms
underpinning sex-dependent longevity are currently unclear. Epigenetic clocks are powerful …

Bats live longer than similar-sized mammals, but the number of lineages that have
independently evolved extreme longevity has not previously been determined. Here we …

Aging, often considered a result of random cellular damage, can be accurately estimated
using DNA methylation profiles, the foundation of pan-tissue epigenetic clocks. Here, we …

Bats possess extraordinary adaptations, including flight, echolocation, extreme longevity
and unique immunity. High-quality genomes are crucial for understanding the molecular …

Aging, for virtually all life, is inescapable. However, within populations, biological aging rates
vary. Understanding sources of variation in this process is central to understanding the …

Naked mole rats (NMRs) live an exceptionally long life, appear not to exhibit age-related
decline in physiological capacity and are resistant to age-related diseases. However, it has …

The evolutionary theory of aging predicts that life span should decrease in response to the
amount of mortality caused by extrinsic sources. Using this prediction, we selected six life …

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Bats make up more than 20% of extant mammals, yet their evolutionary history is largely
unknown because of a limited fossil record and conflicting or incomplete phylogenies. Here …