Neuroinvasion of SARS-CoV-2 in human and mouse brain

E Song, C Zhang, B Israelow, A Lu-Culligan… - Journal of Experimental …, 2021 - rupress.org
Although COVID-19 is considered to be primarily a respiratory disease, SARS-CoV-2 affects
multiple organ systems including the central nervous system (CNS). Yet, there is no …

Evidence of central nervous system infection and neuroinvasive routes, as well as neurological involvement, in the lethality of SARS‐CoV‐2 infection

JM Liu, BH Tan, S Wu, Y Gui, JL Suo… - Journal of medical …, 2021 - Wiley Online Library
The outbreak of coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory
syndrome coronavirus‐2 (SARS‐CoV‐2), has become a significant and urgent threat to …

Evidence of the COVID-19 virus targeting the CNS: tissue distribution, host–virus interaction, and proposed neurotropic mechanisms

AM Baig, A Khaleeq, U Ali, H Syeda - ACS chemical neuroscience, 2020 - ACS Publications
The recent outbreak of coronavirus infectious disease 2019 (COVID-19) has gripped the
world with apprehension and has evoked a scare of epic proportion regarding its potential to …

[PDF][PDF] SARS-CoV-2 targets glial cells in human cortical organoids

CL McMahon, H Staples, M Gazi, R Carrion, J Hsieh - Stem Cell Reports, 2021 - cell.com
Summary Coronavirus disease 2019 (COVID-19) patients have manifested a variety of
neurological complications, and there is still much to reveal regarding the neurotropism of …

Neurological involvements of SARS-CoV2 infection

A Gasmi, T Tippairote, PK Mujawdiya… - Molecular …, 2021 - Springer
COVID-19 is a pandemic viral infection caused by a novel coronavirus, SARS-CoV2, which
is a global concern of the twenty-first century for its rapid spreading in a short period. Apart …

[PDF][PDF] SARS-CoV-2 infects neurons and induces neuroinflammation in a non-human primate model of COVID-19

D Beckman, A Bonillas, GB Diniz, S Ott, JW Roh… - Cell reports, 2022 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiologic agent of
coronavirus disease 2019 (COVID-19), can induce a plethora of neurological complications …

The neurobiology of SARS-CoV-2 infection

J Meinhardt, S Streit, C Dittmayer, RV Manitius… - Nature Reviews …, 2024 - nature.com
Worldwide, over 694 million people have been infected with SARS-CoV-2, with an estimated
55–60% of those infected developing COVID-19. Since the beginning of the pandemic in …

Neuropathology and virus in brain of SARS-CoV-2 infected non-human primates

I Rutkai, MG Mayer, LM Hellmers, B Ning… - Nature …, 2022 - nature.com
Neurological manifestations are a significant complication of coronavirus disease (COVID-
19), but underlying mechanisms aren't well understood. The development of animal models …

SARS‐CoV‐2 targets neurons of 3D human brain organoids

A Ramani, L Müller, PN Ostermann, E Gabriel… - The EMBO …, 2020 - embopress.org
COVID‐19 pandemic caused by SARS‐CoV‐2 infection is a public health emergency.
COVID‐19 typically exhibits respiratory illness. Unexpectedly, emerging clinical reports …

Neurological complications and infection mechanism of SARS-COV-2

D Wan, T Du, W Hong, L Chen, H Que, S Lu… - Signal Transduction and …, 2021 - nature.com
Abstract Currently, SARS-CoV-2 has caused a global pandemic and threatened many lives.
Although SARS-CoV-2 mainly causes respiratory diseases, growing data indicate that SARS …