[HTML][HTML] The predictive significance of a 5-m6A RNA methylation regulator signature in colorectal cancer

D Zhang, G Wu, L Yang, Q Wu, L Yuan - Heliyon, 2023 - cell.com
Colorectal cancer attacks the colon or rectum, with increasing morbidity and mortality
globally. The RNA modification 6-methyladenine (m6A) is related to RNA modifications …

[HTML][HTML] N7-methylguanosine methylation-related regulator genes as biological markers in predicting prognosis for melanoma

J Deng, J Lin, C Liu, J Li, J Cai, X Zhou, X Li - Scientific Reports, 2022 - nature.com
The aim of this study is to find those N7-methylguanosine (m7G) methylation-related
regulator genes (m7GMRRGs) which were associated with melanoma prognosis and use …

Exploring the role of m6A methylation regulators in glioblastoma multiforme and their impact on the tumor immune microenvironment

X Deng, X Sun, Z Hu, Y Wu, C Zhou, J Sun… - The FASEB …, 2023 - Wiley Online Library
Although the role of N6‐Methyladenosine (m6A) methylation factors has been established in
multiple cancer types, its involvement in glioblastoma multiforme (GBM) remains limited …

[HTML][HTML] Estimating the prognosis of esophageal squamous cell carcinoma based on The Cancer Genome Atlas (TCGA) of m6A methylation-associated genes

Y Pu, X Lu, X Yang, Y Yang, D Wang, M Li… - Journal of …, 2022 - ncbi.nlm.nih.gov
Background N6-methyladenosine (m6A) mRNA modification is the most prevalent in certain
tumors. However, its expression profile and prognostic value in human esophageal …

[HTML][HTML] Overview of distinct 5-methylcytosine profiles of messenger RNA in human hepatocellular carcinoma and paired adjacent non-tumor tissues

Q Zhang, Q Zheng, X Yu, Y He, W Guo - Journal of Translational Medicine, 2020 - Springer
Background Post-transcriptional methylation modifications, including 5-methylcytosine
(m5C) modification, are closely related to the tumorigenesis of cancers. However, the mRNA …

[HTML][HTML] DNA methylation-driven genes for developing survival nomogram for low-grade glioma

Y Guo, Y Li, J Li, W Tao, W Dong - Frontiers in Oncology, 2022 - frontiersin.org
Low-grade gliomas (LGG) are heterogeneous, and the current predictive models for LGG
are either unsatisfactory or not user-friendly. The objective of this study was to establish a …

[HTML][HTML] Specific glioma prognostic subtype distinctions based on DNA methylation patterns

X Chen, C Zhao, Z Zhao, H Wang, Z Fang - Frontiers in genetics, 2019 - frontiersin.org
DNA methylation is an important regulator of gene expression and may provide an important
basis for effective glioma diagnosis and therapy. Here, we explored specific prognosis …

[HTML][HTML] N6-methyladenosine regulators promote malignant progression of gastric adenocarcinoma

Y Zhao, X Yan, Y Wang, J Zhou, Y Yu - Frontiers in Oncology, 2022 - frontiersin.org
N6-methyladenosine (m6A) RNA methylation is dynamically and reversibly regulated by
methyltransferases, binding proteins, and demethylases. The restoration of m6A to …

[HTML][HTML] Genome-wide methylation analyses in glioblastoma multiforme

RK Lai, Y Chen, X Guan, D Nousome, C Sharma… - PloS one, 2014 - journals.plos.org
Few studies had investigated genome-wide methylation in glioblastoma multiforme (GBM).
Our goals were to study differential methylation across the genome in gene promoters using …

The Cancer Genome Atlas (TCGA) based m6A methylation-related genes predict prognosis in hepatocellular carcinoma

J Liu, G Sun, S Pan, M Qin, R Ouyang, Z Li… - …, 2020 - Taylor & Francis
The current study aims to investigate the significance of N 6-methyladenosine (m6A)
methylation-related genes in the clinical prognosis of hepatocellular carcinoma (HCC) using …