Important scientific, cultural, temporal, and secular issues impact the development of, and
delivery of vaccines. In this paper we discuss the impact of demographics, regulatory …

Highlights•Vaccines have eradicated smallpox, nearly eradicated polio, and resulted in
99.9% reduction in incidence rates for many diseases.•There are significant challenges …

Why another book about vaccines? There are already a few extremely well-written medical
textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine …

The sciences of vaccinology and of immunology were created just two centuries ago by
Jenner's scientific studies of prevention of smallpox through inoculation with cowpox virus …

Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for
polio, and have profoundly reduced the threat posed by other diseases such as whooping …

Vaccines are considered to be one of the greatest public health achievements of the last
century. Depending on the biology of the infection, the disease to be prevented, and the …

Vaccine Innovations—Past and Future Remarkable progress has been made by the use of
vaccines. The future holds great promise for vaccine-mediated control of global pathogens …

Despite the tremendous success of the classical “isolate, inactivate, and inject” approach to
vaccine development, new breakthroughs in vaccine research are increasingly reliant on …

The Decade of Vaccines Collaboration and development of the Global Vaccine Action Plan
provides a catalyst and unique opportunity for regulators worldwide to develop and propose …

There is an ever-expanding technology that is aimed at making the administration of
vaccines safer. Conventional ways of administering vaccines are being upgraded, modified …