Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

[HTML][HTML] Why does COVID-19 disproportionately affect older people?

AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome …

A Bektas, SH Schurman, C Franceschi, L Ferrucci - Immunity & Ageing, 2020 - Springer
A central clinical question as the world deals with the COVID-19 pandemic is what the long-
term sequelae for the millions of individuals will be who recover from the hyperinflammatory …

Centenarians and COVID-19: is there a link between longevity and better immune defense?

P Kordowitzki - Gerontology, 2022 - karger.com
Dear Editor, The French nun Sister André who is believed to be the world's second-oldest
person was celebrating her 117th birthday on February 11, 2021 after having a SARS-CoV …

SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes

J Nikolich-Zugich, KS Knox, CT Rios, B Natt… - Geroscience, 2020 - Springer
Abstract SARS-CoV-2 virus, the causative agent of the coronavirus infectious disease-19
(COVID-19), is taking the globe by storm, approaching 500,000 confirmed cases and over …

How can biology of aging explain the severity of COVID-19 in older adults

A Gallo, E Pero, S Pellegrino… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
In December 2019 a cluster of pneumonia caused by a previous unknown coronavirus,
SARS-CoV-2, was identified in Wuhan, China. 1 SARS-CoV-2 belongs to the subgenus of …

[HTML][HTML] Aging during the pandemic: untangling the complexities of COVID-19 and geriatric care

K Su, K Jin - Aging and Disease, 2023 - ncbi.nlm.nih.gov
The COVID-19 pandemic has posed unprecedented challenges to the global healthcare
system, with the elderly population being particularly vulnerable. This comprehensive review …

I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

[PDF][PDF] The challenges facing ageing during COVID-19

M Formosa, M Łuszczyńska - Ageing and COVID-19, 2021 - library.oapen.org
The COVID-19 pandemic struck like a lightning on a clear sunny day. When reports surfaced
on the probability of a new pandemic in the first two months of 2020, the public felt no need …