Immunosenescence exacerbates the COVID-19

C Napoli, I Tritto, G Mansueto, E Coscioni… - … of Gerontology and …, 2020 - ncbi.nlm.nih.gov
Aging and senescence are complex processes associated with increased frailty (Calimport,
Bentley, & Stewart, 2019). Overall, many pathogens are more aggressive and prevalent in …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …

[HTML][HTML] All nations must prioritize the COVID-19 vaccination program for elderly adults urgently

C Chakraborty, AR Sharma, M Bhattacharya… - Aging and …, 2021 - ncbi.nlm.nih.gov
Aging increases the risk of infection. The elderly population is susceptible to several
infectious diseases [2]. In the case of COVID-19, more than millions 139 million of infection …

COVID-19 and the elderly: insights into pathogenesis and clinical decision-making

F Perrotta, G Corbi, G Mazzeo, M Boccia… - Aging clinical and …, 2020 - Springer
The elderly may represent a specific cluster of high-risk patients for developing COVID-19
with rapidly progressive clinical deterioration. Indeed, in older individuals …

Aging, immunity, and COVID-19: how age influences the host immune response to coronavirus infections?

V Bajaj, N Gadi, AP Spihlman, SC Wu, CH Choi… - Frontiers in …, 2021 - frontiersin.org
The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

[HTML][HTML] Older adults and COVID-19 pandemic: Resilience matters

LK Chen - Archives of gerontology and geriatrics, 2020 - ncbi.nlm.nih.gov
The coronavirus disease 2019 (COVID-19) pandemic has become a global public health
crisis that results in a great variety of challenges to the world, and the rapidly escalating case …

[HTML][HTML] COVID-19, virology and geroscience: a perspective

C Vellas, P Delobel, PDS Barreto, J Izopet - The journal of nutrition, health …, 2020 - Elsevier
A new coronavirus, called SARS-CoV-2, was identified in Wuhan, China, in December 2019.
The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease …

[HTML][HTML] Coronavirus Disease (COVID-19): a perspective from immunosenescence

M Genebat, L Tarancón-Díez… - Aging and …, 2021 - ncbi.nlm.nih.gov
Since the first reported cases with severe acute respiratory syndrome caused by a novel
coronavirus (SARS-CoV2), this disease called coronavirus disease (COVID-19) has …

Aging and the COVID-19 pandemic: The inter-related roles of biology, physical wellbeing, social norms and global health systems

C Baena, T Joarder, NU Ahmed, R Chowdhury - Maturitas, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic has had a devastating and
disproportionate impact on the elderly population. As the virus has swept through the world …

Immunosenescence and COVID-19

JM Witkowski, T Fulop, E Bryl - Mechanisms of ageing and development, 2022 - Elsevier
Ageing is associated with modified function of both innate and adaptive immunity. It is
believed that changes occurring in ageing immune system are responsible for increased …