Development of quercetin nanoformulation and in vivo evaluation using streptozotocin induced diabetic rat model

D Chitkara, SK Nikalaje, A Mittal, M Chand… - Drug delivery and …, 2012 - Springer
Quercetin-loaded poly (lactic-co-glycolic acid)(PLGA) nanoparticles (Qu-NP) were prepared
by emulsion–diffusion–evaporation method and characterized as 179.9±11.2 nm in size with …

Oral delivery of quercetin to diabetic animals using novel pH responsive carboxypropionylated chitosan/alginate microparticles

P Mukhopadhyay, S Maity, S Chakraborty, R Rudra… - RSC …, 2016 - pubs.rsc.org
This study aims at the development of efficient, biocompatible, biodegradable and bio-safe
polymeric carriers for investigating the pharmaceutical potentialities of bioflavonoid …

Preparation, characterization and in vivo evaluation of pH sensitive, safe quercetin-succinylated chitosan-alginate core-shell-corona nanoparticle for diabetes …

P Mukhopadhyay, S Maity, S Mandal… - Carbohydrate …, 2018 - Elsevier
The study aims for development of an efficient polymeric carrier for evaluating
pharmaceutical potentialities in modulating the drug profile of quercetin (QUE) in anti …

Development and evaluation of PLGA polymer based nanoparticles of quercetin

MK Anwer, MA Al-Mansoor, S Jamil… - International journal of …, 2016 - Elsevier
Quercetin is the most abundant antioxidant found in the human diet. Low aqueous solubility
of quercetin limits its bioavailability and hence therapeutic effects. Therefore, the aim of the …

Development of biodegradable nanoparticles for delivery of quercetin

A Kumari, SK Yadav, YB Pakade, B Singh… - Colloids and Surfaces B …, 2010 - Elsevier
The antioxidant molecule quercetin has been encapsulated on poly-d, l-lactide (PLA)
nanoparticles by solvent evaporation method for the improvement of its poor aqueous …

Poly (n-butylcyanoacrylate) nanoparticles for oral delivery of quercetin: preparation, characterization, and pharmacokinetics and biodistribution studies in Wistar rats

M Bagad, ZA Khan - International journal of nanomedicine, 2015 - Taylor & Francis
Background Quercetin (QT) is a potential bioflavonol and antioxidant with poor
bioavailability and very low distribution in the brain. A new oral delivery system comprising …

Enhancing the potential preclinical and clinical benefits of quercetin through novel drug delivery systems

R Khursheed, SK Singh, S Wadhwa, M Gulati… - Drug discovery today, 2020 - Elsevier
Highlights•Pharmacological activities and molecular targets of quercetin.•Mechanistic
pathways of quercetin for treating different diseases.•Formulation strategies for improving …

[HTML][HTML] Fabrication and evaluation of quercetin nanoemulsion: A delivery system with improved bioavailability and therapeutic efficacy in diabetes mellitus

M Mahadev, HS Nandini, R Ramu, DV Gowda… - Pharmaceuticals, 2022 - mdpi.com
The current study was intended to fabricate and evaluate ultrasonically assisted quercetin
nanoemulsion (Que-NE) for improved bioavailability and therapeutic effectiveness against …

Development and evaluation of biodegradable polymeric nanoparticles for the effective delivery of quercetin using a quality by design approach

VD Kumar, PRP Verma, SK Singh - LWT-Food Science and Technology, 2015 - Elsevier
The aim of the present work is to develop biodegradable polymeric nanoparticles based oral
drug delivery for encapsulation and controlled release of polyphenolic flavonoid (quercetin) …

Development of nanosuspension formulation for oral delivery of quercetin

M Sun, Y Gao, Y Pei, C Guo, H Li, F Cao… - Journal of …, 2010 - ingentaconnect.com
With the aim to enhance dissolution rate and oral bioavailability of quercetin, a poorly water-
soluble drug, quercetin loaded nanosuspension (QT-NS) was fabricated by a tandem of …