T Deng, M Karin - Proceedings of the National Academy of …, 1992 - National Acad Sciences
c-Jun is a typical member of the bZIP (basic zipper) family of dimeric transcriptional activators. These proteins contain a basic region responsible for DNA sequence recognition …
The c-jun and c-fos proto-oncogenes encode proteins that form a complex which regulates transcription from promoters containing AP-1 activation elements. c&n has specific DNA …
D Bohmann, TJ Bos, A Admon, T Nishimura, PK Vogt… - Science, 1987 - science.org
Nuclear oncogene products have the potential to induce alterations in gene regulation leading to the genesis of cancer. The biochemical mechanisms by which nuclear …
K Ryder, D Nathans - … of the National Academy of Sciences, 1988 - National Acad Sciences
We have previously reported that one of the genes that is rapidly induced in mouse 3T3 cells by serum growth factors (jun-B) encodes a protein related to the onco-protein v-jun. By using …
The human proto-oncogene product, cJun, is a member of the AP-1 family of transcription factors, which mediate the regulation of gene expression in response to extracellular …
This study analyzed the post-translational regulation of the transcription factor AP-1 on the level of c-Jun phosphorylation. For this purpose a new assay system employing a histidine …
K Ryder, A Lanahan… - Proceedings of the …, 1989 - National Acad Sciences
The protooncogene c-jun encodes a component of the transcription factor AP-1. Both murine c-jun and a related gene (jun-B) are rapidly activated in BALB/c3T3 cells by serum growth …
Expression of the transcription complex AP-1, composed of Jun and Fos family members, can be induced by a variety of stimuli. In lymphocytes, AP-1 transcriptional activity increases …
K Adachi, H Saito - The Journal of clinical investigation, 1992 - Am Soc Clin Investig
The proliferative effects of granulocyte colony-stimulating factor (G-CSF) and macrophage colony-stimulating factor (M-CSF) on human hematopoietic cells have been reported, but the …