Identification of NF‐jun, a novel inducible transcription factor that regulates c‐jun gene transcription.

MA Brach, F Herrmann, H Yamada, PA Bäuerle… - The EMBO …, 1992 - embopress.org
In this study we report the identification of a novel transcription factor, termed Nuclear Factor‐
jun (NF‐jun). This factor contributes to inducible transcription of the c‐jun gene in human …

Construction and expression of a monomeric c-Jun protein that binds and activates transcription of AP-1-responsive genes.

T Deng, M Karin - Proceedings of the National Academy of …, 1992 - National Acad Sciences
c-Jun is a typical member of the bZIP (basic zipper) family of dimeric transcriptional
activators. These proteins contain a basic region responsible for DNA sequence recognition …

c-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinities

TD Halazonetis, K Georgopoulos, ME Greenberg… - Cell, 1988 - cell.com
The c-jun and c-fos proto-oncogenes encode proteins that form a complex which regulates
transcription from promoters containing AP-1 activation elements. c&n has specific DNA …

Human Proto-Oncogene c-jun Encodes a DNA Binding Protein with Structural and Functional Properties of Transcription Factor AP-1

D Bohmann, TJ Bos, A Admon, T Nishimura, PK Vogt… - Science, 1987 - science.org
Nuclear oncogene products have the potential to induce alterations in gene regulation
leading to the genesis of cancer. The biochemical mechanisms by which nuclear …

Induction of protooncogene c-jun by serum growth factors.

K Ryder, D Nathans - … of the National Academy of Sciences, 1988 - National Acad Sciences
We have previously reported that one of the genes that is rapidly induced in mouse 3T3 cells
by serum growth factors (jun-B) encodes a protein related to the onco-protein v-jun. By using …

Biochemical analysis of transcriptional activation by Jun: differential activity of c-and v-Jun

D Bohmann, R Tjian - Cell, 1989 - cell.com
The human proto-oncogene product, cJun, is a member of the AP-1 family of transcription
factors, which mediate the regulation of gene expression in response to extracellular …

c-Jun phosphorylation in signal transduction and gene regulation.

AG Papavassiliou - Anticancer research, 1993 - europepmc.org
This study analyzed the post-translational regulation of the transcription factor AP-1 on the
level of c-Jun phosphorylation. For this purpose a new assay system employing a histidine …

jun-D: a third member of the jun gene family.

K Ryder, A Lanahan… - Proceedings of the …, 1989 - National Acad Sciences
The protooncogene c-jun encodes a component of the transcription factor AP-1. Both murine
c-jun and a related gene (jun-B) are rapidly activated in BALB/c3T3 cells by serum growth …

Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription.

D Petrak, SA Memon, MJ Birrer, JD Ashwell… - … (Baltimore, Md.: 1950 …, 1994 - journals.aai.org
Expression of the transcription complex AP-1, composed of Jun and Fos family members,
can be induced by a variety of stimuli. In lymphocytes, AP-1 transcriptional activity increases …

Induction of junB expression, but not c-jun, by granulocyte colony-stimulating factor or macrophage colony-stimulating factor in the proliferative response of human …

K Adachi, H Saito - The Journal of clinical investigation, 1992 - Am Soc Clin Investig
The proliferative effects of granulocyte colony-stimulating factor (G-CSF) and macrophage
colony-stimulating factor (M-CSF) on human hematopoietic cells have been reported, but the …