[HTML][HTML] COVID-19 severity is predicted by earlier evidence of accelerated aging
With no known treatments or vaccine, COVID-19 presents a major threat, particularly to older
adults, who account for the majority of severe illness and deaths. The age-related …
adults, who account for the majority of severe illness and deaths. The age-related …
Biological aging predicts vulnerability to COVID-19 severity in UK Biobank participants
Background Age and disease prevalence are the 2 biggest risk factors for Coronavirus
disease 2019 (COVID-19) symptom severity and death. We therefore hypothesized that …
disease 2019 (COVID-19) symptom severity and death. We therefore hypothesized that …
Increased pace of aging in COVID-related mortality
Identifying prognostic biomarkers and risk stratification for COVID-19 patients is a
challenging necessity. One of the core survival factors is patient age. However …
challenging necessity. One of the core survival factors is patient age. However …
[HTML][HTML] Why does COVID-19 disproportionately affect older people?
AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
Adaptive metabolic and inflammatory responses identified using accelerated aging metrics are linked to adverse outcomes in severe SARS-CoV-2 infection
A Márquez-Salinas, CA Fermín-Martínez… - The Journals of …, 2021 - academic.oup.com
Background Chronological age (CA) is a predictor of adverse coronavirus disease 2019
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
(COVID-19) outcomes; however, CA alone does not capture individual responses to severe …
Biomarkers of ageing and frailty may predict COVID-19 severity
KJ Wanhella, C Fernandez-Patron - Ageing research reviews, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is caused by the novel coronavirus, Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
Aging in COVID-19: Vulnerability, immunity and intervention
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic was first
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
reported in Wuhan, China in December 2019, moved across the globe at an unprecedented …
Age-specific COVID-19 case-fatality rate: no evidence of changes over time
C Signorelli, A Odone - International journal of public health, 2020 - Springer
More than 5 months after the World Health Organization (WHO) declared the coronavirus
infectious disease 2019 (COVID-19) outbreak a pandemic, and almost 900,000 deaths …
infectious disease 2019 (COVID-19) outbreak a pandemic, and almost 900,000 deaths …
Genetic and phenotypic analysis of the causal relationship between aging and COVID-19
Background Epidemiological studies revealed that the elderly and those with comorbidities
are most affected by COVID-19, but it is important to investigate shared genetic mechanisms …
are most affected by COVID-19, but it is important to investigate shared genetic mechanisms …
COVID-19 mortality as a fingerprint of biological age
Abstract Corona virus disease 2019 (COVID-19) is a global emergency able to overwhelm
the healthcare capacities worldwide and to affect the older generation especially. When …
the healthcare capacities worldwide and to affect the older generation especially. When …