Alzheimer's and Parkinson's diseases predict different COVID-19 outcomes: a UK Biobank study

Y Yu, M Travaglio, R Popovic, NS Leal, LM Martins - Geriatrics, 2021 - mdpi.com
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID …

Assessing the age specificity of infection fatality rates for COVID-19: Meta-analysis & public policy implications

AT Levin, KB Cochran, SP Walsh - medRxiv, 2020 - medrxiv.org
This paper assesses the age specificity of the infection fatality rate (IFR) for COVID-19. Our
benchmark meta-regression synthesizes the age-specific IFRs from four recent large-scale …

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: considerations beyond chronological …

OY Bello-Chavolla, A González-Díaz… - The Journals of …, 2021 - academic.oup.com
Background COVID-19 has had a disproportionate impact on older adults. Mexico's
population is younger, yet COVID-19's impact on older adults is comparable to countries …

The 90 plus: longevity and COVID-19 survival

M Zatz, MVR Silva, MV de Castro, MS Naslavsky - Molecular Psychiatry, 2022 - nature.com
The world population is getting older and studies aiming to enhance our comprehension of
the underlying mechanisms responsible for health span are of utmost interest for longevity …

Age-related changes in plasma biomarkers and their association with mortality in COVID-19

EHA Michels, B Appelman… - European …, 2023 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly
in older patients. Several immunomodulating therapies seem less beneficial in these …

Five reasons COVID-19 is less severe in younger age-groups

PW Turke - Evolution, Medicine, and Public Health, 2021 - academic.oup.com
The severity of COVID-19 is age-related, with the advantage going to younger age-groups.
Five reasons are presented. The first two are well-known, are being actively researched by …

Age and COVID-19 mortality

I Sasson - Demographic Research, 2021 - JSTOR
BACKGROUND Demographers have emphasized the importance of age in explaining the
spread of COVID-19 and its impact on mortality. However, the relationship between COVID …

[HTML][HTML] SARS-CoV-2, immunosenescence and inflammaging: partners in the COVID-19 crime

R Domingues, A Lippi, C Setz, TF Outeiro… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Pneumonia outbreak in the city of Wuhan, China, prompted the finding of a novel strain of
severe acute respiratory syndrome virus (SARS-CoV-2). Here, we discuss potential long …

A geroscience perspective on COVID-19 mortality

DEL Promislow - The journals of gerontology: Series A, 2020 - academic.oup.com
A novel coronavirus, SARS-CoV-2, emerged in December 2019, leading within a few
months to a global pandemic. COVID-19, the disease caused by this highly contagious virus …

Severe COVID-19 patients exhibit elevated levels of autoantibodies targeting cardiolipin and platelet glycoprotein with age: a systems biology approach

DLM Fonseca, IS Filgueiras, AHC Marques, E Vojdani… - npj Aging, 2023 - nature.com
Age is a significant risk factor for the coronavirus disease 2019 (COVID-19) severity due to
immunosenescence and certain age-dependent medical conditions (eg, obesity …