Frailty as a risk factor for post‐acute sequelae of COVID‐19 among US veterans during the Delta and Omicron waves

IS Hammel, DM Tosi, F Tang, H Pott… - Journal of the American …, 2023 - Wiley Online Library
Background Older populations have suffered the highest rates of SARS‐CoV‐2 infection
and associated complications, including Post‐Acute Sequelae of SARS‐CoV‐2 infection …

Accelerated immune ageing is associated with COVID-19 disease severity

JM Lord, T Veenith, J Sullivan, A Sharma-Oates… - Immunity & …, 2024 - Springer
Background The striking increase in COVID-19 severity in older adults provides a clear
example of immunesenescence, the age-related remodelling of the immune system. To …

Severe COVID-19 is associated with molecular signatures of aging in the human brain

M Mavrikaki, JD Lee, IH Solomon, FJ Slack - Nature Aging, 2022 - nature.com
Abstract As coronavirus disease 2019 (COVID-19) and aging are both accompanied by
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …

Age-dependent effects in the transmission and control of COVID-19 epidemics

NG Davies, P Klepac, Y Liu, K Prem, M Jit, RM Eggo - Nature medicine, 2020 - nature.com
The COVID-19 pandemic has shown a markedly low proportion of cases among children,,–.
Age disparities in observed cases could be explained by children having lower susceptibility …

Age could be driving variable SARS-CoV-2 epidemic trajectories worldwide

HH Ayoub, H Chemaitelly, S Seedat, GR Mumtaz… - PLoS …, 2020 - journals.plos.org
Current geographic spread of documented severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infections shows heterogeneity. This study explores the role of age in …

Cellular senescence as a potential mediator of COVID‐19 severity in the elderly

J Nehme, M Borghesan, S Mackedenski, TG Bird… - Aging cell, 2020 - Wiley Online Library
SARS‐CoV‐2 is a novel betacoronavirus which infects the lower respiratory tract and can
cause coronavirus disease 2019 (COVID‐19), a complex respiratory distress syndrome …

COVID-19 and quarantine, a catalyst for ageism

N Barth, J Guyot, SA Fraser, M Lagacé… - Frontiers in public …, 2021 - frontiersin.org
In February 2021, France had more than 76,000 deaths due to COVID-19 and older adults
were heavily affected. Most measures taken to reduce the impact of COVID-19 (quarantine …

The age-related risk of severe outcomes due to COVID-19 infection: a rapid review, meta-analysis, and meta-regression

K Romero Starke, G Petereit-Haack… - International journal of …, 2020 - mdpi.com
Increased age appears to be a strong risk factor for COVID-19 severe outcomes. However,
studies do not sufficiently consider the age-dependency of other important factors …

Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors

X Gu, S Wang, W Zhang, C Li, L Guo, Z Wang, H Li… - …, 2023 - thelancet.com
Background As a debilitating condition that can impact a whole spectrum of people and
involve multi-organ systems, long COVID has aroused the most attention than ever …

Pandemic research for older people: doing it better next time

MD Witham, AL Gordon, EJ Henderson… - Age and …, 2021 - academic.oup.com
The coronavirus disease 2019 (COVID-19) pandemic has disproportionately affected older
people, both in terms of hospitalizations and deaths, but also by the consequences of …